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Descriptor English: F-Box Proteins
Descriptor Spanish: Proteínas F-Box
Descriptor proteínas F-box
Entry term(s) familia de proteínas F-Box
proteína F-Box
proteína con dominio F-Box
Scope note: Familia de proteínas que comparten el motivo F-box y que intervienen en las interacciones proteína-proteína. Desempeñan un importante papel en los procesos de ubicuitinación proteínica mediante la asociación con diversos substratos que, a su vez, forman complejos de SCF-UBICUITINA-LIGASA. Estas proteínas se mantienen en los complejos ubicuitina-ligasa al unirse a proteínas con un dominio SKP.
Descriptor Portuguese: Proteínas F-Box
Descriptor French: Protéines F-box
Entry term(s): Domain Protein, F-Box
F Box Domain Protein
F Box Protein
F Box Protein Family
F Box Proteins
F-Box Domain Protein
F-Box Protein
F-Box Protein Family
Protein Family, F-Box
Protein, F-Box
Protein, F-Box Domain
Tree number(s): D12.776.157.169
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D044783
Scope note: A family of proteins that share the F-BOX MOTIF and are involved in protein-protein interactions. They play an important role in the process of protein ubiquition by associating with a variety of substrates and then associating into SCF UBIQUITIN LIGASE complexes. They are held in the ubiquitin-ligase complex via binding to SKP DOMAIN PROTEINS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2004
History Note: 2004
Related: F-Box Motifs MeSH
DeCS ID: 38252
Unique ID: D044783
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2004/01/01
Date of Entry: 2003/07/09
Revision Date: 2020/05/27
F-Box Proteins - Preferred
Concept UI M0446216
Scope note A family of proteins that share the F-BOX MOTIF and are involved in protein-protein interactions. They play an important role in the process of protein ubiquition by associating with a variety of substrates and then associating into SCF UBIQUITIN LIGASE complexes. They are held in the ubiquitin-ligase complex via binding to SKP DOMAIN PROTEINS.
Preferred term F-Box Proteins
Entry term(s) Domain Protein, F-Box
F Box Domain Protein
F Box Protein
F Box Protein Family
F Box Proteins
F-Box Domain Protein
F-Box Protein
F-Box Protein Family
Protein Family, F-Box
Protein, F-Box
Protein, F-Box Domain



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