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Descriptor English: Phosphatidylethanolamine Binding Protein
Descriptor Spanish: Proteínas de Unión a Fosfatidiletanolamina
Descriptor proteína de unión a la fosfatidiletanolamina
Entry term(s) proteína que se une a la fosfatidiletanolamina
Scope note: Proteína básica ubicua que se une a la fosfatidiletanolamina y a NUCLEÓTIDOS. Es un inhibidor endógeno de QUINASAS RAF y puede tener un papel en la regulación de la TRANSDUCCIÓN DE SEÑALES. La proteína que se une a la fosfatidiletanolamina es el precursor del péptido neuroestimulante colinérgico del hipocampo, que es escindido de la región N-terminal de la proteína.
Descriptor Portuguese: Proteína de Ligação a Fosfatidiletanolamina
Descriptor French: Protéine de liaison de phosphatidyl-éthanolamine
Entry term(s): HCNP Precursor Protein
Hippocampal Cholinergic Neurostimulating Peptide Precursor
Phosphatidylethanolamine-Binding Protein
Raf Kinase Inhibitor Protein
Tree number(s): D12.644.360.562
D12.776.157.661
D12.776.476.555
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D049488
Scope note: A ubiquitously found basic protein that binds to phosphatidylethanolamine and NUCLEOTIDES. It is an endogenous inhibitor of RAF KINASES and may play a role in regulating SIGNAL TRANSDUCTION. Phosphatidylethanolamine-binding protein is the precursor of hippocampal cholinergic neurostimulating peptide, which is cleaved from the N-terminal region of the protein.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Protein Kinase Inhibitors
Previous Indexing: Carrier Proteins (2000-2004)
Public MeSH Note: 2005; PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN was indexed under CARRIER PROTEINS 2000-2004
History Note: 2005(2000)
DeCS ID: 38751
Unique ID: D049488
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2005/01/01
Date of Entry: 2004/07/07
Revision Date: 2015/11/24
Phosphatidylethanolamine Binding Protein - Preferred
Concept UI M0074920
Scope note A ubiquitously found basic protein that binds to phosphatidylethanolamine and NUCLEOTIDES. It is an endogenous inhibitor of RAF KINASES and may play a role in regulating SIGNAL TRANSDUCTION. Phosphatidylethanolamine-binding protein is the precursor of hippocampal cholinergic neurostimulating peptide, which is cleaved from the N-terminal region of the protein.
Preferred term Phosphatidylethanolamine Binding Protein
Entry term(s) HCNP Precursor Protein
Hippocampal Cholinergic Neurostimulating Peptide Precursor
Phosphatidylethanolamine-Binding Protein
Raf Kinase Inhibitor Protein



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