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Descriptor English: Focal Adhesion Kinase 2
Descriptor Spanish: Quinasa 2 de Adhesión Focal
Descriptor cinasa de adhesión focal 2
Entry term(s) cinasa 2 de adherencia focal
quinasa 2 de adherencia focal
quinasa 2 de adhesión focal
Scope note: Proteína-tirosina cinasa no receptora que se expresa principalmente en el CEREBRO, los OSTEOBLASTOS y las CÉLULAS LINFOIDES. En el SISTEMA NERVIOSO CENTRAL la cinasa 2 de adhesión focal modula la función de los CANALES IÓNICOS y la actividad de las PROTEINCINASAS ACTIVADAS POR MITÓGENOS.
Descriptor Portuguese: Quinase 2 de Adesão Focal
Descriptor French: Focal adhesion kinase 2
Entry term(s): CADTK Protein
Calcium Dependent Protein Tyrosine Kinase
Calcium-Dependent Protein Tyrosine Kinase
Cell Adhesion Kinase Beta
FAK Autokinase
Focal Adhesion Kinase Autokinase
PYK2 Protein Tyrosine Kinase
Proline Rich Tyrosine Kinase 2
Proline-Rich Tyrosine Kinase 2
Protein Tyrosine Kinase PYK2
RAFTK Protein
Related Adhesion Focal Tyrosine Kinase
Tree number(s): D08.811.913.696.620.682.725.049.750
D12.776.476.568.049.750
D23.050.301.500.600.350
D23.050.705.552.600.350
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D051418
Scope note: A non-receptor protein-tyrosine kinase that is expressed primarily in the BRAIN; OSTEOBLASTS; and LYMPHOID CELLS. In the CENTRAL NERVOUS SYSTEM focal adhesion kinase 2 modulates ION CHANNEL function and MITOGEN-ACTIVATED PROTEIN KINASES activity.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.7.10.2
Public MeSH Note: 2006; FOCAL ADHESION KINASE 2 was indexed under PROTEIN-TYROSINE KINASE 1995-2005
History Note: 2006(1995)
DeCS ID: 50730
Unique ID: D051418
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2016/02/26
Focal Adhesion Kinase 2 - Preferred
Concept UI M0251076
Scope note A non-receptor protein-tyrosine kinase that is expressed primarily in the BRAIN; OSTEOBLASTS; and LYMPHOID CELLS. In the CENTRAL NERVOUS SYSTEM focal adhesion kinase 2 modulates ION CHANNEL function and MITOGEN-ACTIVATED PROTEIN KINASES activity.
Preferred term Focal Adhesion Kinase 2
Entry term(s) CADTK Protein
Calcium Dependent Protein Tyrosine Kinase
Calcium-Dependent Protein Tyrosine Kinase
Cell Adhesion Kinase Beta
FAK Autokinase
Focal Adhesion Kinase Autokinase
PYK2 Protein Tyrosine Kinase
Proline Rich Tyrosine Kinase 2
Proline-Rich Tyrosine Kinase 2
Protein Tyrosine Kinase PYK2
RAFTK Protein
Related Adhesion Focal Tyrosine Kinase



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