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Descriptor English: E2F4 Transcription Factor
Descriptor Spanish: Factor de Transcripción E2F4
Descriptor factor de transcripción E2F4
Scope note: Factor de transcripción E2F que reprime la TRANSCRIPCIÓN GENÉTICA necesaria para la entrada en el CICLO CELULAR y la síntesis de ADN. El factor E2F4 recluta indirectamente factores de remodelación de la cromatina para actuar en REGIONES PROMOTORAS de genes, merced a la PROTEÍNA P130 SIMILAR A LA DEL RETINOBLASTOMA y la PROTEÍNA P107 SIMILAR A LA DEL RETINOBLASTOMA.
Descriptor Portuguese: Fator de Transcrição E2F4
Descriptor French: Facteur de transcription E2F4
Entry term(s): E2F 4 Protein
E2F 4 Transcription Factor
E2F Transcription Factor 4 Protein
E2F-4 Protein
E2F-4 Transcription Factor
E2F-4, Transcription Factor
Transcription Factor E2F 4
Transcription Factor E2F-4
Transcription Factor, E2F-4
Transcription Factor, E2F4
Tree number(s): D12.776.930.211.812
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D050704
Scope note: An E2F transcription factor that represses GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis. E2F4 recruits chromatin remodeling factors indirectly to target gene PROMOTER REGIONS through RETINOBLASTOMA LIKE PROTEIN P130 and RETINOBLASTOMA LIKE PROTEIN P107.
Annotation: see SCR for organism-specific terms
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: DNA-Binding Proteins (1994-2005)
Transcription Factors (1994-2005)
Public MeSH Note: 2006; E2F4 TRANSCRIPTION FACTOR was indexed under DNA-BINDING PROTEINS & TRANSCRIPTION FACTORS 1994-2005
History Note: 2006(1994)
DeCS ID: 51184
Unique ID: D050704
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2016/05/27
E2F4 Transcription Factor - Preferred
Concept UI M0239285
Scope note An E2F transcription factor that represses GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis. E2F4 recruits chromatin remodeling factors indirectly to target gene PROMOTER REGIONS through RETINOBLASTOMA LIKE PROTEIN P130 and RETINOBLASTOMA LIKE PROTEIN P107.
Preferred term E2F4 Transcription Factor
Entry term(s) E2F 4 Protein
E2F 4 Transcription Factor
E2F Transcription Factor 4 Protein
E2F-4 Protein
E2F-4 Transcription Factor
E2F-4, Transcription Factor
Transcription Factor E2F 4
Transcription Factor E2F-4
Transcription Factor, E2F-4
Transcription Factor, E2F4



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