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Descriptor English: E2F1 Transcription Factor
Descriptor Spanish: Factor de Transcripción E2F1
Descriptor factor de transcripción E2F1
Scope note: Factor de transcripción E2F que interactúa directamente con la PROTEÍNA DEL RETINOBLASTOMA y la CICLINA A, y activa la TRANSCRIPCIÓN GENÉTICA necesaria para la entrada en el CICLO CELULAR y la síntesis de ADN. El factor E2F1 está relacionado con la REPARACIÓN DEL ADN y con la APOPTOSIS.
Descriptor Portuguese: Fator de Transcrição E2F1
Descriptor French: Facteur de transcription E2F1
Entry term(s): E2F Transcription Factor 1 Protein
E2F-1 Transcription Factor
Retinoblastoma Associated Protein 1
Retinoblastoma Binding Protein 3
Retinoblastoma-Associated Protein 1
Transcription Factor E2F 1
Transcription Factor E2F-1
Transcription Factor E2F1
Transcription Factor, E2F-1
Transcription Factor, E2F1
Tree number(s): D12.644.360.024.328.049
D12.776.157.057.158.049
D12.776.476.024.420.049
D12.776.660.769.049
D12.776.930.211.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D050687
Scope note: An E2F transcription factor that interacts directly with RETINOBLASTOMA PROTEIN and CYCLIN A and activates GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis. E2F1 is involved in DNA REPAIR and APOPTOSIS.
Annotation: see SCR for organism-specific terms
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Cell Cycle Proteins (1991-2005)
DNA-Binding Proteins (1991-2005)
Transcription Factors (1991-2005)
Public MeSH Note: 2006; E2F TRANSCRIPTION FACTORS was indexed under CELL CYCLE PROTEINS; DNA-BINDING PROTEINS; & TRANSCRIPTION FACTORS 1991-2005
History Note: 2006(1991)
DeCS ID: 51181
Unique ID: D050687
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2016/04/28
E2F1 Transcription Factor - Preferred
Concept UI M0188999
Scope note An E2F transcription factor that interacts directly with RETINOBLASTOMA PROTEIN and CYCLIN A and activates GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis. E2F1 is involved in DNA REPAIR and APOPTOSIS.
Preferred term E2F1 Transcription Factor
Entry term(s) E2F Transcription Factor 1 Protein
E2F-1 Transcription Factor
Retinoblastoma Associated Protein 1
Retinoblastoma Binding Protein 3
Retinoblastoma-Associated Protein 1
Transcription Factor E2F 1
Transcription Factor E2F-1
Transcription Factor E2F1
Transcription Factor, E2F-1
Transcription Factor, E2F1



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