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Descriptor English: E2F Transcription Factors
Descriptor Spanish: Factores de Transcripción E2F
Descriptor factores de transcripción E2F
Entry term(s) factor de transcripción E2F
Scope note: Familia de factores de transcripción con motivo hélice-bucle-hélice que controlan la expresión de diversos GENES involucrados en la regulación del CICLO CELULAR. Los factores de transcripción E2F forman típicamente complejos heterodiméricos con el FACTOR DE TRANSCRIPCIÓN DP1 o con el factor de transcripción DP2, y presentan un dominio N-terminal de unión al ADN y un dominio de dimerización. Los factores de transcripción E2F pueden actuar como mediadores en la represión o en la activación transcripcional.
Descriptor Portuguese: Fatores de Transcrição E2F
Descriptor French: Facteurs de transcription E2F
Entry term(s): E2F Proteins
E2F Transcription Factor
E2F, Transcription Factor
Factor, E2F Transcription
Transcription Factor E2F
Transcription Factor, E2F
Transcription Factors, E2F
Tree number(s): D12.776.930.211
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D050684
Scope note: A family of basic helix-loop-helix transcription factors that control expression of a variety of GENES involved in CELL CYCLE regulation. E2F transcription factors typically form heterodimeric complexes with TRANSCRIPTION FACTOR DP1 or transcription factor DP2, and they have N-terminal DNA binding and dimerization domains. E2F transcription factors can act as mediators of transcriptional repression or transcriptional activation.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Cell Cycle Proteins (1991-2005)
DNA-Binding Proteins (1991-2005)
Transcription Factors (1991-2005)
Public MeSH Note: 2006; E2F TRANSCRIPTION FACTORS was indexed under CELL CYCLE PROTEINS, DNA-BINDING PROTEINS, & TRANSCRIPTION FACTORS 1991-2005
History Note: 2006(1991)
DeCS ID: 51180
Unique ID: D050684
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2020/05/27
E2F Transcription Factors - Preferred
Concept UI M0189005
Scope note A family of basic helix-loop-helix transcription factors that control expression of a variety of GENES involved in CELL CYCLE regulation. E2F transcription factors typically form heterodimeric complexes with TRANSCRIPTION FACTOR DP1 or transcription factor DP2, and they have N-terminal DNA binding and dimerization domains. E2F transcription factors can act as mediators of transcriptional repression or transcriptional activation.
Preferred term E2F Transcription Factors
Entry term(s) E2F Proteins
E2F Transcription Factor
E2F, Transcription Factor
Factor, E2F Transcription
Transcription Factor E2F
Transcription Factor, E2F
Transcription Factors, E2F



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