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Descriptor English: E2F6 Transcription Factor
Descriptor Spanish: Factor de Transcripción E2F6
Descriptor factor de transcripción E2F6
Scope note: Factor de transcripción E2F que reprime la TRANSCRIPCIÓN GENÉTICA necesaria para la entrada en el CICLO CELULAR y la síntesis de ADN. El factor E2F6 recluta directamente factores de remodelación de cromatina para actuar en los genes promotores y carece del dominio de transactivación responsable de la unión a supresores tumorales de la familia del retinoblastoma.
Descriptor Portuguese: Fator de Transcrição E2F6
Descriptor French: Facteur de transcription E2F6
Entry term(s): E2F Transcription Factor 6 Protein
E2F-6, Transcription Factor
Transcription Factor E2F 6
Transcription Factor E2F-6
Transcription Factor, E2F6
Tree number(s): D12.776.930.211.937
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D050701
Scope note: An E2F transcription factor that represses GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis. E2F6 recruits chromatin remodeling factors directly to target gene promoters and lacks the transactivation domain responsible for binding to the retinoblastoma family of tumor suppressors.
Annotation: see SCR for organism-specific terms
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Cell Cycle Proteins (1991-2005)
DNA-Binding Proteins (1991-2005)
Transcription Factors (1991-2005)
Public MeSH Note: 2006; E2F6 TRANSCRIPTION FACTOR, E2F TRANSCRIPTION FACTOR 6 PROTEIN, & TRANSCRIPTION FACTOR E2F-6 were indexed under DNA-BINDING PROTEINS & TRANSCRIPTIONS FACTORS 2004-2005
History Note: 2006(2004)
DeCS ID: 51186
Unique ID: D050701
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2016/05/27
E2F6 Transcription Factor - Preferred
Concept UI M0477187
Scope note An E2F transcription factor that represses GENETIC TRANSCRIPTION required for CELL CYCLE entry and DNA synthesis. E2F6 recruits chromatin remodeling factors directly to target gene promoters and lacks the transactivation domain responsible for binding to the retinoblastoma family of tumor suppressors.
Preferred term E2F6 Transcription Factor
Entry term(s) E2F Transcription Factor 6 Protein
E2F-6, Transcription Factor
Transcription Factor E2F 6
Transcription Factor E2F-6
Transcription Factor, E2F6



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