| Descriptor English: | Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein | ||||||
| Descriptor Spanish: |
Proteína 1 de la Translocación del Linfoma del Tejido Linfático Asociado a Mucosas
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| Descriptor Portuguese: | Proteína de Translocação 1 do Linfoma de Tecido Linfoide Associado à Mucosa | ||||||
| Descriptor French: | Protéine-1 de translocation de lymphome du tissu lymphoïde associé aux muqueuses | ||||||
| Entry term(s): |
MALT 1 Protein MALT-1 Protein MALT1 Paracaspase MALT1 Protein Mucosa Associated Lymphoid Tissue Lymphoma Translocation 1 Protein Paracaspase Paracaspase, MALT1 |
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| Tree number(s): |
D08.811.277.656.262.500.126.775 D08.811.277.656.300.200.126.775 D08.811.464.938.750.233 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000074884 | ||||||
| Scope note: | A caspase-like cysteine endopeptidase that also exhibits ubiquitin ligase activity. It contains an N-terminal DEATH DOMAIN, two IMMUNOGLOBULIN-LIKE DOMAINS, and localizes to the perinuclear region of MONOCYTES, where it functions in activation of NF-KAPPA B; it also binds to and activates TRAF6. Chromosomal translocations involving the MALT1 and BIRC2 genes are associated with MALT LYMPHOMA, and mutations in the MALT1 gene are associated with Type 12 IMMUNODEFICIENCY SYNDROMES. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 3.4.22.- | ||||||
| Previous Indexing: |
Caspases (1999-2017) Neoplasm Proteins (1999-2017) |
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| Public MeSH Note: | 2018 |
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| History Note: | 2018 |
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| DeCS ID: | 57006 | ||||||
| Unique ID: | D000074884 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2018/01/01 | ||||||
| Date of Entry: | 2017/07/11 | ||||||
| Revision Date: | 2017/05/22 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes
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Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein
- Preferred
| Concept UI |
M000628332 |
| Scope note | A caspase-like cysteine endopeptidase that also exhibits ubiquitin ligase activity. It contains an N-terminal DEATH DOMAIN, two IMMUNOGLOBULIN-LIKE DOMAINS, and localizes to the perinuclear region of MONOCYTES, where it functions in activation of NF-KAPPA B; it also binds to and activates TRAF6. Chromosomal translocations involving the MALT1 and BIRC2 genes are associated with MALT LYMPHOMA, and mutations in the MALT1 gene are associated with Type 12 IMMUNODEFICIENCY SYNDROMES. |
| Preferred term | Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein |
| Entry term(s) |
MALT 1 Protein MALT-1 Protein MALT1 Paracaspase MALT1 Protein Mucosa Associated Lymphoid Tissue Lymphoma Translocation 1 Protein Paracaspase Paracaspase, MALT1 |
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