Search
Descriptor English: Caspase 12
Descriptor Spanish: Caspasa 12
Descriptor caspasa 12
Entry term(s) CASP12
Scope note: Caspasa con un prodominio largo que contiene un dominio de reclutamiento de caspasa en su región prodominio. La caspasa 12 es activada por factores proapoptósicos liberados en el estrés celular y mediante PROTEÍNAS ADAPTADORAS DE SEÑALIZACIÓN CARD. Activa la APOPTOSIS mediante escisión y activación de CASPASAS EFECTORAS.
Descriptor Portuguese: Caspase 12
Descriptor French: Caspase-12
Entry term(s): Caspase-12
Tree number(s): D08.811.277.656.262.500.126.550.920
D08.811.277.656.300.200.126.550.920
D12.776.476.075.405.550.920
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053454
Scope note: A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Caspase 12 is activated by pro-apoptotic factors that are released during cell stress and by CARD SIGNALING ADAPTOR PROTEINS. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: antagonists & inhibitors:Caspase Inhibitors
Registry Number: EC 3.4.22.-
Public MeSH Note: 2007; CASPASE 12 was indexed under CASPASES 2000-2005
History Note: 2007(2000)
DeCS ID: 52230
Unique ID: D053454
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2016/07/05
Caspase 12 - Preferred
Concept UI M0355943
Scope note A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Caspase 12 is activated by pro-apoptotic factors that are released during cell stress and by CARD SIGNALING ADAPTOR PROTEINS. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.
Preferred term Caspase 12
Entry term(s) Caspase-12



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey