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Descriptor in English: Leukemia Inhibitory Factor
Descriptor in Spanish: Factor Inhibidor de Leucemia
Descriptor in Portuguese: Fator Inibidor de Leucemia
Descriptor in French: Facteur inhibiteur de la leucémie
Entry term(s): AM424
Cholinergic Differentiation Factor
D Factor (Leukemia Inhibitory Factor)
Differentiation Factor, Cholinergic
Differentiation Stimulating Factor
Differentiation-Stimulating Factor
Differentiation-Stimulating Factor, Myeloid
Emfilermin
Inhibitory Factor, Leukemia
Myeloid Differentiation Stimulating Factor
Myeloid Differentiation-Stimulating Factor
Tree number(s): D12.644.276.374.470
D12.776.467.374.470
D23.529.374.470
Scope note: An INTERLEUKIN-6 related cytokine that exhibits pleiotrophic effects on many physiological systems that involve cell proliferation, differentiation, and survival. Leukemia inhibitory factor binds to and acts through the lif receptor.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
History Note: 2007(1980)
DeCS UI: 52282
Descriptor UI: D053605
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2016/07/01
Leukemia Inhibitory Factor - Preferred
Concept UI M0097307
Scope note An INTERLEUKIN-6 related cytokine that exhibits pleiotrophic effects on many physiological systems that involve cell proliferation, differentiation, and survival. Leukemia inhibitory factor binds to and acts through the lif receptor.
Preferred term Leukemia Inhibitory Factor
Entry term(s) Cholinergic Differentiation Factor
D Factor (Leukemia Inhibitory Factor)
Differentiation Factor, Cholinergic
Differentiation Stimulating Factor
Differentiation-Stimulating Factor
Differentiation-Stimulating Factor, Myeloid
Inhibitory Factor, Leukemia
Myeloid Differentiation Stimulating Factor
Myeloid Differentiation-Stimulating Factor
Emfilermin - Narrower
Concept UI M0471288
Preferred term Emfilermin
AM424 - Narrower
Concept UI M0097294
Preferred term AM424



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