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Descriptor English: Oncostatin M
Descriptor Spanish: Oncostatina M
Descriptor oncostatina M
Scope note: Citocina con acciones proinflamatorias y antiinflamatorias que dependen del microambiente celular. La oncostatina M es una glucoproteína monomérica de 28 kDa con una estructura similar a la del FACTOR INHIBIDOR DE LA LEUCEMIA. Su nombre proviene de la observación de que inhibe el crecimiento de las células tumorales y aumenta el crecimiento de los fibroblastos normales.
Descriptor Portuguese: Oncostatina M
Descriptor French: Oncostatine M
Tree number(s): D12.644.276.374.562
D12.776.467.374.562
D23.529.374.562
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053683
Scope note: A cytokine with both pro- and anti-inflammatory actions that depend upon the cellular microenvironment. Oncostatin M is a 28 kDa monomeric glycoprotein that is similar in structure to LEUKEMIA INHIBITORY FACTOR. Its name derives from the the observation that it inhibited the growth of tumor cells and augmented the growth of normal fibroblasts.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Pharm Action: Antineoplastic Agents
Growth Inhibitors
Registry Number: 106956-32-5
CAS Type 1 Name: Oncostatin M
Public MeSH Note: 2007; ONCOSTATIN M was indexed under CYTOKINES 1987-2006
History Note: 2007(1987)
DeCS ID: 52283
Unique ID: D053683
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Oncostatin M - Preferred
Concept UI M0145692
Scope note A cytokine with both pro- and anti-inflammatory actions that depend upon the cellular microenvironment. Oncostatin M is a 28 kDa monomeric glycoprotein that is similar in structure to LEUKEMIA INHIBITORY FACTOR. Its name derives from the the observation that it inhibited the growth of tumor cells and augmented the growth of normal fibroblasts.
Preferred term Oncostatin M



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