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Descriptor in English: Interferons
Descriptor in Spanish: Interferones
Descriptor in Portuguese: Interferons
Descriptor in French: Interférons
Entry term(s): Interferon
Tree number(s): D12.644.276.374.440
D12.776.467.374.440
D23.529.374.440
Scope note: Proteins secreted by vertebrate cells in response to a wide variety of inducers. They confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions.
Annotation: "stimulators" or "inducers" = INTERFERON INDUCERS
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Online Note: use INTERFERONS to search INTERFERON 1966-82
History Note: 83; was INTERFERON 1963-82
See also the descriptors: Receptors, Interferon MeSH
DeCS UI: 29469
Descriptor UI: D007372
Date Established: 1983/01/01
Date of Entry: 1999/01/01
Revision Date: 2015/06/22
Interferons - Preferred
Concept UI M0011491
Scope note Proteins secreted by vertebrate cells in response to a wide variety of inducers. They confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions.
Preferred term Interferons
Entry term(s) Interferon



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