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Descriptor English: Growth Differentiation Factor 15
Descriptor Spanish: Factor 15 de Diferenciación de Crecimiento
Descriptor factor 15 de diferenciación del crecimiento
Entry term(s) GDF-15
Scope note: Factor de diferenciación del crecimiento que se secreta en respuesta al estrés celular y en respuesta a la ACTIVACIÓN DE MACRÓFAGOS. Además, el factor 15 de diferenciación del crecimiento muestra una amplia gama de propiedades biológicas, como la inducción de formación de cartílago, la inhibición de la proliferación de progenitores hematopoyéticos y la inducción de la migración neuronal. 
Descriptor Portuguese: Fator 15 de Diferenciação de Crescimento
Descriptor French: Facteur-15 de croissance et de différenciation
Entry term(s): Differentiation Factor, Prostate
GDF-15
Macrophage Inhibitory Cytokine 1
Prostate Differentiation Factor
Tree number(s): D12.644.276.374.305
D12.644.276.954.300.915
D12.776.467.374.305
D12.776.467.942.300.915
D23.529.374.305
D23.529.942.300.915
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D055436
Scope note: A growth differentiation factor that is secreted in response to cell stress and in response to MACROPHAGE ACTIVATION. In addition growth differentiation factor 15 demonstrates a diverse array of biological properties including the induction of cartilage formation, the inhibition of hematopoietic progenitor proliferation, and the induction of neuronal migration.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2009; GROWTH DIFFERENTIATION FACTOR 15 was indexed under CYTOKINES 1997-2008
History Note: 2009(1997)
DeCS ID: 53127
Unique ID: D055436
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2009/01/01
Date of Entry: 2008/07/08
Growth Differentiation Factor 15 - Preferred
Concept UI M0282507
Scope note A growth differentiation factor that is secreted in response to cell stress and in response to MACROPHAGE ACTIVATION. In addition growth differentiation factor 15 demonstrates a diverse array of biological properties including the induction of cartilage formation, the inhibition of hematopoietic progenitor proliferation, and the induction of neuronal migration.
Preferred term Growth Differentiation Factor 15
Entry term(s) Differentiation Factor, Prostate
GDF-15
Macrophage Inhibitory Cytokine 1
Prostate Differentiation Factor



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