Search
Descriptor English: Edar-Associated Death Domain Protein
Descriptor Spanish: Proteína de Dominio de Muerte Asociada a Edar
Descriptor proteína del dominio de muerte asociada a edar
Scope note: Factor asociado al receptor del factor de necrosis tumoral que actúa como proteína adaptadora de señalización específica para el RECEPTOR EDAR y desempeña un papel importante en el desarrollo ectodérmico. Se une al receptor edar por medio de la región del dominio de muerte C-terminal y a otros factores específicos asociados con recepores de TNF por medio del dominio N- terminal. La pérdida de función de la proteína del dominio de muerte asociada a edar se asocia con DISPLASIA ECTODÉRMICA ANHIDRÓTICA AUTOSÓMICA RECESIVA.
Descriptor Portuguese: Proteína de Domínio de Morte Associada a Edar
Descriptor French: Protéine à domaine de mort associée à Edar
Entry term(s): Edar Associated Death Domain Protein
Edaradd Protein
Tree number(s): D12.644.360.024.285.100
D12.644.360.024.500.061
D12.644.360.075.421.100
D12.776.157.057.018.100
D12.776.157.057.500.061
D12.776.476.024.320.100
D12.776.476.024.500.061
D12.776.476.075.421.100
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053362
Scope note: A tumor necrosis factor receptor-associated factor that acts as a specific signaling adaptor protein for the EDAR RECEPTOR and plays an important role in ectodermal development. It binds to edar receptor via its C-terminal death domain region and to other specific TNF receptor-associated factors via its N-terminal domain. Loss of function of edar-associated death domain protein is associated with AUTOSOMAL RECESSIVE ANHIDROTIC ECTODERMAL DYSPLASIA.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: deficiency:Ectodermal Dysplasia, Hypohidrotic, Autosomal Recessive
Public MeSH Note: 2007; EDAR-ASSOCIATED DEATH DOMAIN PROTEIN was indexed under TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED PEPTIDES AND PROTEINS 2002-2006
History Note: 2007(2002)
DeCS ID: 52310
Unique ID: D053362
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2017/05/24
Edar-Associated Death Domain Protein - Preferred
Concept UI M0492748
Scope note A tumor necrosis factor receptor-associated factor that acts as a specific signaling adaptor protein for the EDAR RECEPTOR and plays an important role in ectodermal development. It binds to edar receptor via its C-terminal death domain region and to other specific TNF receptor-associated factors via its N-terminal domain. Loss of function of edar-associated death domain protein is associated with AUTOSOMAL RECESSIVE ANHIDROTIC ECTODERMAL DYSPLASIA.
Preferred term Edar-Associated Death Domain Protein
Entry term(s) Edar Associated Death Domain Protein
Edaradd Protein



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.

Go to survey