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Descriptor English: Receptor-Interacting Protein Serine-Threonine Kinases
Descriptor Spanish: Proteína Serina-Treonina Quinasas de Interacción con Receptores
Descriptor proteínas serina-treonina cinasas de interacción con receptores
Entry term(s) serina treonina cinasas interactuantes con receptores
serina-treonina cinasas RIP
Scope note: Familia de serina-treonina cinasas que interviene en la transducción de señales intracelulares por interacción con diversas proteínas adaptadoras de señalización, tales como la PROTEÍNA ADAPTADORA DE SEÑALIZACIÓN CRADD, FACTOR 2 ASOCIADO AL RECEPTOR DE TNF, y PROTEÍNA DE DOMINIO DE MUERTE ASOCIADA AL RECEPTOR DE TNF. Aunque fueron descritas inicialmente como proteínas adaptadoras de unión al dominio de muerte, los miembros de esta familia pueden contener otros dominios de unión a proteínas tales como los que implican la activación y reclutamiento de caspasas.
Descriptor Portuguese: Proteína Serina-Treonina Quinases de Interação com Receptores
Descriptor French: Receptor-Interacting Protein Serine-Threonine Kinases
Entry term(s): Kinase, RIP Serine-Threonine
Kinases, RIP Serine-Threonine
RIP (Receptor Interacting Protein)
RIP Serine Threonine Kinase
RIP Serine Threonine Kinases
RIP Serine-Threonine Kinase
RIP Serine-Threonine Kinases
Receptor Interacting Protein RIP
Receptor Interacting Protein Serine Threonine Kinase 1
Receptor Interacting Protein Serine Threonine Kinase 3
Receptor Interacting Protein Serine Threonine Kinases
Receptor-Interacting Protein Serine-Threonine Kinase 1
Receptor-Interacting Protein Serine-Threonine Kinase 3
Serine-Threonine Kinase, RIP
Serine-Threonine Kinases, RIP
Tree number(s): D08.811.913.696.620.682.700.801
D12.776.157.057.018.400
D12.776.157.057.500.186
D12.776.476.024.320.662
D12.776.476.024.500.186
D12.776.476.075.421.400
D12.776.476.563.801
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053422
Scope note: A family of serine-threonine kinases that plays a role in intracellular signal transduction by interacting with a variety of signaling adaptor proteins such as CRADD SIGNALING ADAPTOR PROTEIN; TNF RECEPTOR-ASSOCIATED FACTOR 2; and TNF RECEPTOR-ASSOCIATED DEATH DOMAIN PROTEIN. Although they were initially described as death domain-binding adaptor proteins, members of this family may contain other protein-binding domains such as those involving caspase activation and recruitment.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.7.11.1
Public MeSH Note: 2007; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES was indexed under PROTEIN-SERINE THREONINE KINASES & TUMOR NECROSIS FACTOR RECEPTOR-ASSOCIATED PROTEINS 2006, & under PROTEINS 1995-2006
History Note: 2007(1995)
DeCS ID: 52250
Unique ID: D053422
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2017/05/24
Receptor-Interacting Protein Serine-Threonine Kinases - Preferred
Concept UI M0492994
Scope note A family of serine-threonine kinases that plays a role in intracellular signal transduction by interacting with a variety of signaling adaptor proteins such as CRADD SIGNALING ADAPTOR PROTEIN; TNF RECEPTOR-ASSOCIATED FACTOR 2; and TNF RECEPTOR-ASSOCIATED DEATH DOMAIN PROTEIN. Although they were initially described as death domain-binding adaptor proteins, members of this family may contain other protein-binding domains such as those involving caspase activation and recruitment.
Preferred term Receptor-Interacting Protein Serine-Threonine Kinases
Entry term(s) Kinases, RIP Serine-Threonine
RIP Serine Threonine Kinases
RIP Serine-Threonine Kinases
Receptor Interacting Protein Serine Threonine Kinases
Serine-Threonine Kinases, RIP
Receptor-Interacting Protein Serine-Threonine Kinase 3 - Narrower
Concept UI M0493000
Preferred term Receptor-Interacting Protein Serine-Threonine Kinase 3
Entry term(s) Receptor Interacting Protein Serine Threonine Kinase 3
Receptor-Interacting Protein Serine-Threonine Kinase 1 - Narrower
Concept UI M0492996
Preferred term Receptor-Interacting Protein Serine-Threonine Kinase 1
Entry term(s) Kinase, RIP Serine-Threonine
RIP (Receptor Interacting Protein)
RIP Serine Threonine Kinase
RIP Serine-Threonine Kinase
Receptor Interacting Protein RIP
Receptor Interacting Protein Serine Threonine Kinase 1
Serine-Threonine Kinase, RIP



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