Descriptor English: | Fas-Associated Death Domain Protein | ||||
Descriptor Spanish: |
Proteína de Dominio de Muerte Asociada a Fas
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Descriptor Portuguese: | Proteína de Domínio de Morte Associada a Fas | ||||
Descriptor French: | Protéine à domaine de mort associée à Fas | ||||
Entry term(s): |
FADD Protein, Fas Associating FADD Protein, Fas-Associating FADD, Fas-Associating Protein Fas Associated Death Domain Protein Fas Associating Protein FADD Fas Associating Protein with Death Domain Fas-Associating FADD Protein Fas-Associating Protein FADD Fas-Associating Protein with Death Domain MORT1 Protein |
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Tree number(s): |
D12.644.360.024.285.200 D12.644.360.024.500.124 D12.644.360.075.421.200 D12.776.157.057.018.200 D12.776.157.057.500.124 D12.776.476.024.320.550 D12.776.476.024.500.124 D12.776.476.075.421.200 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D053200 | ||||
Scope note: | A signal-transducing adaptor protein that associates with TNF RECEPTOR complexes. It contains a death effector domain that can interact with death effector domains found on INITIATOR CASPASES such as CASPASE 8 and CASPASE 10. Activation of CASPASES via interaction with this protein plays a role in the signaling cascade that leads to APOPTOSIS. |
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Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Public MeSH Note: | 2007; FAS-ASSOCIATED DEATH DOMAIN PROTEIN was indexed under ADAPTOR PROTEINS, SIGNAL TRANSDUCING 2005 & under CARRIER PROTEINS 1995-2004 |
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History Note: | 2007(1995) |
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DeCS ID: | 52311 | ||||
Unique ID: | D053200 | ||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
Date Established: | 2007/01/01 | ||||
Date of Entry: | 2006/07/05 | ||||
Revision Date: | 2017/05/24 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Fas-Associated Death Domain Protein
- Preferred
Concept UI |
M0245371 |
Scope note | A signal-transducing adaptor protein that associates with TNF RECEPTOR complexes. It contains a death effector domain that can interact with death effector domains found on INITIATOR CASPASES such as CASPASE 8 and CASPASE 10. Activation of CASPASES via interaction with this protein plays a role in the signaling cascade that leads to APOPTOSIS. |
Preferred term | Fas-Associated Death Domain Protein |
Entry term(s) |
FADD Protein, Fas Associating FADD Protein, Fas-Associating FADD, Fas-Associating Protein Fas Associated Death Domain Protein Fas Associating Protein FADD Fas Associating Protein with Death Domain Fas-Associating FADD Protein Fas-Associating Protein FADD Fas-Associating Protein with Death Domain MORT1 Protein |
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