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Descriptor English: Tumor Necrosis Factor Receptor Superfamily, Member 9
Descriptor Spanish: Miembro 9 de la Superfamilia de Receptores de Factores de Necrosis Tumoral
Descriptor miembro 9 de la superfamilia de receptores del factor de necrosis tumoral
Entry term(s) antígeno CD137
antígenos CD137
receptor TNFRSF9
receptores 4-1BB
Scope note: Miembro de la superfamilia de receptores de factores de necrosis tumoral, específico para el LIGANDO 4-1BB. Se encuentra en diversos tipos de células inmunes, como los LINFOCITOS-T activados, las CÉLULAS ASESINAS NATURALES y las CÉLULAS DENDRÍTICAS. La activación del receptor en los LINFOCITOS-T interviene en su expansión, producción de citoquinas y supervivencia. La señalización por el receptor activado se produce merced a su asociación con los FACTORES ASOCIADOS A RECEPTORES TNF.
Descriptor Portuguese: Membro 9 da Superfamília de Receptores de Fatores de Necrose Tumoral
Descriptor French: Antigènes CD137
Entry term(s): 4 1BB Receptor
4 1BB Receptors
4-1BB Receptor
4-1BB Receptors
Antigen, CD137
Antigens, CD137
CD137 Antigen
CD137 Antigens
Receptor, 4-1BB
Receptor, TNFRSF9
Receptors, 4-1BB
TNFRSF9 Receptor
Tree number(s): D12.776.543.750.705.852.760.220
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053261
Scope note: A member of the tumor necrosis factor receptor superfamily that is specific for 4-1BB LIGAND. It is found in a variety of immune cell types including activated T-LYMPHOCYTES; NATURAL KILLER CELLS; and DENDRITIC CELLS. Activation of the receptor on T-LYMPHOCYTES plays a role in their expansion, production of cytokines and survival. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
Allowable Qualifiers: AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Public MeSH Note: 2007; see ANTIGENS, CD137 2007-2017; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY, MEMBER 9 was indexed under RECEPTORS, TUMOR NECROSIS FACTOR; RECEPTORS, NERVE GROWTH FACTOR and ANTIGENS, CD 1993-2006
History Note: 2018 (1993)
DeCS ID: 52384
Unique ID: D053261
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2017/05/24
Tumor Necrosis Factor Receptor Superfamily, Member 9 - Preferred
Concept UI M0214853
Scope note A member of the tumor necrosis factor receptor superfamily that is specific for 4-1BB LIGAND. It is found in a variety of immune cell types including activated T-LYMPHOCYTES; NATURAL KILLER CELLS; and DENDRITIC CELLS. Activation of the receptor on T-LYMPHOCYTES plays a role in their expansion, production of cytokines and survival. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
Preferred term Tumor Necrosis Factor Receptor Superfamily, Member 9
Entry term(s) 4 1BB Receptor
4 1BB Receptors
4-1BB Receptor
4-1BB Receptors
Antigen, CD137
Antigens, CD137
CD137 Antigen
CD137 Antigens
Receptor, 4-1BB
Receptor, TNFRSF9
Receptors, 4-1BB
TNFRSF9 Receptor



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