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Descriptor English: Receptor Activator of Nuclear Factor-kappa B
Descriptor Spanish: Receptor Activador del Factor Nuclear kappa-B
Descriptor activador del receptor del factor nuclear kappa B
Entry term(s) activador del receptor del NF-kappa B
antígeno CD265
miembro 11a de la superfamilia de receptores del factor de necrosis tumoral
miembro 11a de los receptores del factor de necrosis tumoral
Scope note: Miembro de la familia de receptores del factor de necrosis tumoral que es específico para el LIGANDO RANK e interviene en la homeostasis regulando la osteoclastogénesis. También se expresa en las CÉLULAS DENDRÍTICAS, donde juega un papel regulando la supervivencia de la célula dendrítica. La señalización por el receptor activado se produce merced a su asociación con FACTORES ASOCIADOS AL RECEPTOR DE TNF.
Descriptor Portuguese: Receptor Ativador de Fator Nuclear kappa-B
Descriptor French: Récepteur activateur du facteur nucléaire Kappa B
Entry term(s): Activator, NF-KappaB Receptor
Antigen, CD265
CD265 Antigen
NF Kappa B Receptor Activator
NF KappaB Receptor Activator
NF-Kappa B Receptor Activator
NF-KappaB Receptor Activator
RANK Protein
Receptor Activator of NF kappa B
Receptor Activator of NF kappaB
Receptor Activator of NF-kappa B
Receptor Activator of NF-kappaB
Receptor Activator of Nuclear Factor kappa B
Receptor Activator of Nuclear Factor kappaB
Receptor Activator of Nuclear Factor-kappaB
Receptor Activator, NF-KappaB
Receptors, Tumor Necrosis Factor, Member 11a
TNFRSF11A Protein
TRANCE R
TRANCE Receptor
TRANCE-R
Tumor Necrosis Factor Receptor Superfamily, Member 11a
Tree number(s): D12.776.543.750.705.852.760.345
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053246
Scope note: A tumor necrosis factor receptor family member that is specific for RANK LIGAND and plays a role in bone homeostasis by regulating osteoclastogenesis. It is also expressed on DENDRITIC CELLS where it plays a role in regulating dendritic cell survival. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2007; for RECEPTORS, TUMOR NECROSIS FACTOR, MEMBER 11A see GLYCOPROTEINS; RECEPTORS, TUMOR NECROSIS FACTOR; & RECEPTORS, CYTOPLASMIC AND NUCLEAR 1997-2005
History Note: 2007(1997)
DeCS ID: 52389
Unique ID: D053246
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2017/05/24
Receptor Activator of Nuclear Factor-kappa B - Preferred
Concept UI M0371270
Scope note A tumor necrosis factor receptor family member that is specific for RANK LIGAND and plays a role in bone homeostasis by regulating osteoclastogenesis. It is also expressed on DENDRITIC CELLS where it plays a role in regulating dendritic cell survival. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
Preferred term Receptor Activator of Nuclear Factor-kappa B
Entry term(s) Activator, NF-KappaB Receptor
Antigen, CD265
CD265 Antigen
NF Kappa B Receptor Activator
NF KappaB Receptor Activator
NF-Kappa B Receptor Activator
NF-KappaB Receptor Activator
RANK Protein
Receptor Activator of NF kappa B
Receptor Activator of NF kappaB
Receptor Activator of NF-kappa B
Receptor Activator of NF-kappaB
Receptor Activator of Nuclear Factor kappa B
Receptor Activator of Nuclear Factor kappaB
Receptor Activator of Nuclear Factor-kappaB
Receptor Activator, NF-KappaB
Receptors, Tumor Necrosis Factor, Member 11a
TNFRSF11A Protein
TRANCE R
TRANCE Receptor
TRANCE-R
Tumor Necrosis Factor Receptor Superfamily, Member 11a



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