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Descriptor English: Receptors, Tumor Necrosis Factor, Member 14
Descriptor Spanish: Miembro 14 de Receptores del Factor de Necrosis Tumoral
Descriptor miembro 14 de los receptores de factores de necrosis tumoral
Entry term(s) mediador de la entrada del herpesvirus
miembro 14 de la superfamilia de receptores del factor de necrosis tumoral
Scope note: Nuevo miembro de la familia de receptores del factor de necrosis tumoral, que también puede mediar en la entrada en la célula del VIRUS DEL HERPES SIMPLE TIPO 1. Posee especificidad para el MIEMBRO 14 DE LA SUPERFAMILIA DE LIGANDOS DEL FACTOR DE NECROSIS TUMORAL y la forma isotrimérica de LINFOTOXINA-ALFA. Este receptor se expresa abundantemente en los LINFOCITOS-T y puede intervenir regulando la activación linfocítica. La señal del receptor se activa merced a su asociación con FACTORES ASOCIADOS AL RECEPTOR DE TNF.
Descriptor Portuguese: Membro 14 de Receptores do Fator de Necrose Tumoral
Descriptor French: Membre-14 de la superfamille des récepteurs au TNF
Entry term(s): Entry Mediator, Herpesvirus
HVEM Protein
Herpesvirus Entry Mediator
HveA Protein
Tumor Necrosis Factor Receptor Subfamily, Member 14
Tumor Necrosis Factor Receptor Superfamily, Member 14
Tree number(s): D12.776.543.750.705.852.760.500
D12.776.543.750.830.850
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D053240
Scope note: A novel member of the tumor-necrosis factor receptor family that can also mediate HERPES SIMPLEX VIRUS TYPE 1 entry into cells. It has specificity for TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14 and the homotrimeric form of LYMPHOTOXIN-ALPHA. The receptor is abundantly expressed on T-LYMPHOCYTES and may play a role in regulating lymphocyte activation. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2007; RECEPTORS, TUMOR NECROSIS FACTOR, MEMBER 14 was indexed under RECEPTORS, VIRUS & RECEPTORS, TUMOR NECROSIS FACTOR 1997-2006
History Note: 2007(1997)
DeCS ID: 52393
Unique ID: D053240
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2007/01/01
Date of Entry: 2006/07/05
Revision Date: 2016/06/17
Receptors, Tumor Necrosis Factor, Member 14 - Preferred
Concept UI M0277012
Scope note A novel member of the tumor-necrosis factor receptor family that can also mediate HERPES SIMPLEX VIRUS TYPE 1 entry into cells. It has specificity for TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14 and the homotrimeric form of LYMPHOTOXIN-ALPHA. The receptor is abundantly expressed on T-LYMPHOCYTES and may play a role in regulating lymphocyte activation. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
Preferred term Receptors, Tumor Necrosis Factor, Member 14
Entry term(s) Entry Mediator, Herpesvirus
HVEM Protein
Herpesvirus Entry Mediator
HveA Protein
Tumor Necrosis Factor Receptor Subfamily, Member 14
Tumor Necrosis Factor Receptor Superfamily, Member 14



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