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Descriptor English: Group III Phospholipases A2
Descriptor Spanish: Fosfolipasas A2 Grupo III
Descriptor fosfolipasas A2 del grupo III
Scope note: Subcategoría de fosfolipasas A2 secretadas con especificidad por la FOSFATIDILETANOLAMINA y la FOSFATIDILCOLINA. Forma parte de diversos VENENOS y de la fosfolipasa A2 secretora de mamíferos. La creación de este grupo se basa en similitudes en los determinantes estructurales de las enzimas que incluyen un largo dominio amino-terminal, un dominio específico del grupo III conservado y un largo dominio carboxi-terminal.
Descriptor Portuguese: Fosfolipases A2 do Grupo III
Descriptor French: Group III Phospholipases A2
Entry term(s): Group III Secretory Phospholipase A2
Phospholipase A2 III
Phospholipase A2-III
Phospholipases A2, Group III
Tree number(s): D08.811.277.352.100.680.750.937.750.662
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D054520
Scope note: A subcategory of secreted phospholipases A2 with specificity for PHOSPHATIDYLETHANOLAMINES and PHOSPHATIDYLCHOLINE. It occurs as a component of VENOMS and as a mammalian secretory phospholipase A2. The creation of this group is based upon similarities in the structural determinants of the enzymes including a long amino-terminal domain, a conserved group III-specific domain, and a long carboxyl-terminal domain.
Annotation: /antag: coordinate with PHOSPHOLIPASE A2 INHIBITORS
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.1.1.4
Previous Indexing: Phospholipases A (1980-2007)
Public MeSH Note: 2008
History Note: 2008
DeCS ID: 52672
Unique ID: D054520
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 2013/07/08
Group III Phospholipases A2 - Preferred
Concept UI M0505824
Scope note A subcategory of secreted phospholipases A2 with specificity for PHOSPHATIDYLETHANOLAMINES and PHOSPHATIDYLCHOLINE. It occurs as a component of VENOMS and as a mammalian secretory phospholipase A2. The creation of this group is based upon similarities in the structural determinants of the enzymes including a long amino-terminal domain, a conserved group III-specific domain, and a long carboxyl-terminal domain.
Preferred term Group III Phospholipases A2
Entry term(s) Group III Secretory Phospholipase A2
Phospholipase A2 III
Phospholipase A2-III
Phospholipases A2, Group III



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