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Descriptor English: Group X Phospholipases A2
Descriptor Spanish: Fosfolipasas A2 Grupo X
Descriptor fosfolipasas A2 del grupo X
Scope note: Subtipo de fosfolipasa A2 secretada que contiene una región de unión interfacial con especificidad por la FOSFATIDILCOLINA. Este grupo de enzimas puede intervenir en la liberación de ÁCIDO ARAQUIDÓNICO de las membranas celulares intactas y de las LIPOPROTEÍNAS DE BAJA DENSIDAD. Los miembros de este grupo se unen específicamente a los RECEPTORES DE FOSFOLIPASA A2.
Descriptor Portuguese: Fosfolipases A2 do Grupo X
Descriptor French: Group X phospholipases A2
Entry term(s): GX sPLA(2)
Group X Secretory Phospholipase A(2)
Group X Secretory Phospholipase A2
Phospholipase A2, Group X
Phospholipases A2, Group X
sPLA(2)-X
sPLA2-X
Tree number(s): D08.811.277.352.100.680.750.937.750.887
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D054509
Scope note: A secreted phospholipase A2 subtype that contains a interfacial-binding region with specificity for PHOSPHATIDYLCHOLINE. This enzyme group may play a role in eliciting ARACHIDONIC ACID release from intact cellular membranes and from LOW DENSITY LIPOPROTEINS. Members of this group bind specifically to PHOSPHOLIPASE A2 RECEPTORS.
Annotation: /antag: coordinate with PHOSPHOLIPASE A2 INHIBITORS
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.1.1.4
Public MeSH Note: 2008; GROUP X PHOSPHOLIPASES A2 was indexed under PHOSPHOLIPASES A 2002-2007
History Note: 2008(2002)
DeCS ID: 52674
Unique ID: D054509
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 2013/07/08
Group X Phospholipases A2 - Preferred
Concept UI M0410905
Scope note A secreted phospholipase A2 subtype that contains a interfacial-binding region with specificity for PHOSPHATIDYLCHOLINE. This enzyme group may play a role in eliciting ARACHIDONIC ACID release from intact cellular membranes and from LOW DENSITY LIPOPROTEINS. Members of this group bind specifically to PHOSPHOLIPASE A2 RECEPTORS.
Preferred term Group X Phospholipases A2
Entry term(s) GX sPLA(2)
Group X Secretory Phospholipase A(2)
Group X Secretory Phospholipase A2
Phospholipase A2, Group X
Phospholipases A2, Group X
sPLA(2)-X
sPLA2-X



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