| Descriptor English: | Phospholipases A2, Secretory | ||||||
| Descriptor Spanish: |
Fosfolipasas A2 Secretoras
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| Descriptor Portuguese: | Fosfolipases A2 Secretórias | ||||||
| Descriptor French: | Secretory Phospholipases A2 | ||||||
| Entry term(s): |
A2, Secreted Phospholipase Phospholipase A2, Secreted Phospholipase A2, Secretory Phospholipases A2, Secreted Phospholipases, SPLA2 SPLA2 Phospholipases Secreted Phospholipase A2 Secreted Phospholipases A2 Secretory Phospholipase A2 Secretory Phospholipases A2 sPLA(2) sPLA2 sPLA2s |
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| Tree number(s): |
D08.811.277.352.100.680.750.937.750 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D054497 | ||||||
| Scope note: | A subcategory of phospholipases A2 that are secreted from cells. They are 14 kDa proteins containing multiple disulfide-bonds and access their substrate via an interfacial binding site that interacts with phospholipid membranes. In addition specific PHOSPHOLIPASE A2 RECEPTORS can bind to and internalize the enzymes. |
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| Annotation: | /antag: coordinate with PHOSPHOLIPASE A2 INHIBITORS |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Registry Number: | EC 3.1.1.4 | ||||||
| Previous Indexing: |
Phospholipases A (1980-2007) |
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| Public MeSH Note: | 2008; SECRETORY PHOSPHOLIPASE A2 was indexed under PHOSPHOLIPASES A 1998-2007 |
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| History Note: | 2008 |
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| DeCS ID: | 52667 | ||||||
| Unique ID: | D054497 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2008/01/01 | ||||||
| Date of Entry: | 2007/07/09 | ||||||
| Revision Date: | 2020/06/25 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes
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Phospholipases A2, Secretory
- Preferred
| Concept UI |
M0505572 |
| Scope note | A subcategory of phospholipases A2 that are secreted from cells. They are 14 kDa proteins containing multiple disulfide-bonds and access their substrate via an interfacial binding site that interacts with phospholipid membranes. In addition specific PHOSPHOLIPASE A2 RECEPTORS can bind to and internalize the enzymes. |
| Preferred term | Phospholipases A2, Secretory |
| Entry term(s) |
A2, Secreted Phospholipase Phospholipase A2, Secreted Phospholipase A2, Secretory Phospholipases A2, Secreted Phospholipases, SPLA2 SPLA2 Phospholipases Secreted Phospholipase A2 Secreted Phospholipases A2 Secretory Phospholipase A2 Secretory Phospholipases A2 sPLA(2) sPLA2 sPLA2s |
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