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Descriptor English: Group V Phospholipases A2
Descriptor Spanish: Fosfolipasas A2 Grupo V
Descriptor fosfolipasas A2 del grupo V
Scope note: Subcategoría de fosfolipasas A2 segregadas que contiene un segmento carboxi terminal cargado negativamente y una región de unión interfacial específica para las membranas que contienen FOSFATIDIL COLINA. Este grupo enzimático puede intervenir en la liberación de ÁCIDO ARAQUIDÓNICO de las membranas fosfolipídicas.
Descriptor Portuguese: Fosfolipases A2 do Grupo V
Descriptor French: Group V Phospholipases A2
Entry term(s): Group V Secretory Phospholipase A2
Group V sPLA2
Phospholipases A2, Group V
Tree number(s): D08.811.277.352.100.680.750.937.750.775
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D054505
Scope note: A subcategory of secreted phospholipases A2 that contains both a negatively charged carboxy-terminal segment and interfacial-binding region specific for PHOSPHATIDYL CHOLINE-containing membranes. This enzyme group may play a role in the release of ARACHIDONIC ACID from phospholipid membranes.
Annotation: /antag: coordinate with PHOSPHOLIPASE A2 INHIBITORS
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.1.1.4
Public MeSH Note: 2008; GROUP V SECRETORY PHOSPHOLIPASE A2 was indexed under PHOSPHOLIPASES A 2001-2007
History Note: 2008(2001)
DeCS ID: 52673
Unique ID: D054505
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 2013/07/08
Group V Phospholipases A2 - Preferred
Concept UI M0375732
Scope note A subcategory of secreted phospholipases A2 that contains both a negatively charged carboxy-terminal segment and interfacial-binding region specific for PHOSPHATIDYL CHOLINE-containing membranes. This enzyme group may play a role in the release of ARACHIDONIC ACID from phospholipid membranes.
Preferred term Group V Phospholipases A2
Entry term(s) Group V Secretory Phospholipase A2
Group V sPLA2
Phospholipases A2, Group V



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