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Descriptor English: Dual Specificity Phosphatase 1
Descriptor Spanish: Fosfatasa 1 de Especificidad Dual
Descriptor fosfatasa 1 de doble especificidad
Scope note: Subtipo de fosfatasa de doble especificidad que interviene en la transducción de señales intracelulares al inactivar a las PROTEÍNA CINASAS ACTIVADAS POR MITÓGENOS. Tiene especificidad por las PROTEÍNAS CINASAS P38 ACTIVADAS POR MITÓGENOS y por las PROTEÍNA CINASAS JNK ACTIVADAS POR MITÓGENOS.
Descriptor Portuguese: Fosfatase 1 de Especificidade Dupla
Descriptor French: Dual Specificity Phosphatase 1
Entry term(s): 3CH134 Phosphatase
CL100 Phosphatase
Externally Regulated Phosphatase (ERP)
MAP Phosphatase 1
MAP Phosphatase-1
MAPK Phosphatase
MKP 1 Phosphatase
MKP-1 Phosphatase
Map Kinase Phosphatase 1
Mitogen Activated Protein Phosphatase 1
Mitogen-Activated Protein Phosphatase-1
Phosphatase, 3CH134
Phosphatase, CL100
Phosphatase, MAPK
Phosphatase, MKP-1
Phosphatase-1, MAP
Phosphatase-1, Mitogen-Activated Protein
Protein Phosphatase-1, Mitogen-Activated
Tree number(s): D08.811.277.352.650.587.200
D08.811.277.352.650.625.225.200
D08.811.277.352.650.775.250.200
D08.811.641.755.200
D12.776.476.445.200
D12.776.476.559.225.200
D12.776.476.564.250.200
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D054638
Scope note: A dual specificity phosphatase subtype that plays a role in intracellular signal transduction by inactivating MITOGEN-ACTIVATED PROTEIN KINASES. It has specificity for P38 MITOGEN-ACTIVATED PROTEIN KINASES and JNK MITOGEN-ACTIVATED PROTEIN KINASES.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.1.3.48
Public MeSH Note: 2008; DUAL SPECIFICITY PHOSPHATASE 1 was indexed under CELL CYCLE PROTEINS, IMMEDIATE-EARLY PROTEINS & PHOSPHOPROTEIN PHOSPHATASE 1994-2007, & under PROTEINS 1992-1993
History Note: 2008(1992)
DeCS ID: 52688
Unique ID: D054638
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 2013/07/08
Dual Specificity Phosphatase 1 - Preferred
Concept UI M0197551
Scope note A dual specificity phosphatase subtype that plays a role in intracellular signal transduction by inactivating MITOGEN-ACTIVATED PROTEIN KINASES. It has specificity for P38 MITOGEN-ACTIVATED PROTEIN KINASES and JNK MITOGEN-ACTIVATED PROTEIN KINASES.
Preferred term Dual Specificity Phosphatase 1
Entry term(s) 3CH134 Phosphatase
CL100 Phosphatase
Externally Regulated Phosphatase (ERP)
MAP Phosphatase 1
MAP Phosphatase-1
MAPK Phosphatase
MKP 1 Phosphatase
MKP-1 Phosphatase
Map Kinase Phosphatase 1
Mitogen Activated Protein Phosphatase 1
Mitogen-Activated Protein Phosphatase-1
Phosphatase, 3CH134
Phosphatase, CL100
Phosphatase, MAPK
Phosphatase, MKP-1
Phosphatase-1, MAP
Phosphatase-1, Mitogen-Activated Protein
Protein Phosphatase-1, Mitogen-Activated



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