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Descriptor English: Dual-Specificity Phosphatases
Descriptor Spanish: Fosfatasas de Especificidad Dual
Descriptor fosfatasas de doble especificidad
Scope note: Subclase de proteína tirosina fosfatasas con actividad fosfatasa adicional, con escisión de los enlaces de éster fosfato en los residuos de SERINA y TREONINA que están localizados en la misma proteína.
Descriptor Portuguese: Fosfatases de Especificidade Dupla
Descriptor French: Dual-specificity phosphatases
Entry term(s): DUSP Phosphatases
Dual Specificity Phosphatase
Dual Specificity Phosphatases
Dual-Specificity Phosphatase
Phosphatase, Dual-Specificity
Phosphatases, DUSP
Phosphatases, Dual-Specificity
Tree number(s): D08.811.277.352.650.625.225
D08.811.277.352.650.775.250
D08.811.641.755
D12.776.476.559.225
D12.776.476.564.250
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D054637
Scope note: A sub-class of protein tyrosine phosphatases that contain an additional phosphatase activity which cleaves phosphate ester bonds on SERINE or THREONINE residues that are located on the same protein.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.1.3.48
Previous Indexing: Phosphoprotein Phosphatases (1992-2007)
Protein Tyrosine Phosphatases (1992-2007)
Public MeSH Note: 2008
History Note: 2008
DeCS ID: 52692
Unique ID: D054637
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 2015/11/23
Dual-Specificity Phosphatases - Preferred
Concept UI M0506559
Scope note A sub-class of protein tyrosine phosphatases that contain an additional phosphatase activity which cleaves phosphate ester bonds on SERINE or THREONINE residues that are located on the same protein.
Preferred term Dual-Specificity Phosphatases
Entry term(s) DUSP Phosphatases
Dual Specificity Phosphatase
Dual Specificity Phosphatases
Dual-Specificity Phosphatase
Phosphatase, Dual-Specificity
Phosphatases, DUSP
Phosphatases, Dual-Specificity



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