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Descriptor English: Fatty Acid Synthase, Type I
Descriptor Spanish: Acido Graso Sintasa Tipo I
Descriptor ácido graso sintasa tipo I
Scope note: Forma animal de sintasa de ácidos grasos que es codificada por un único gen y que consta de siete dominios catalíticos y es funcional como homodímero. Se hiperexpresa en algunas NEOPLASIAS y es una diana en humanos de algunos AGENTES ANTINEOPLÁSICOS y de algunos AGENTES ANTIOBESIDAD.
Descriptor Portuguese: Ácido Graxo Sintase Tipo I
Descriptor French: Fatty acid synthase type I
Entry term(s): Fatty Acid Synthase, Animal Form
Fatty Acid Synthase, Mammalian
Tree number(s): D08.811.277.352.897.387.100
D08.811.520.241.300.287.099
D08.811.641.758
D08.811.682.047.820.196.500.099
D08.811.913.050.134.029.500.100
D08.811.913.050.170.500.100
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D054890
Scope note: Animal form of fatty acid synthase which is encoded by a single gene and consists of seven catalytic domains and is functional as a homodimer. It is overexpressed in some NEOPLASMS and is a target in humans of some ANTINEOPLASTIC AGENTS and some ANTI-OBESITY AGENTS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.3.1.85
Previous Indexing: Fatty Acid Synthetase Complex (1971-2007)
Public MeSH Note: 2014; see FATTY ACID SYNTHASE COMPLEX, TYPE I 2008-2013
History Note: 2014(2008)
DeCS ID: 52720
Unique ID: D054890
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 2013/07/08
Fatty Acid Synthase, Type I - Preferred
Concept UI M0508620
Scope note Animal form of fatty acid synthase which is encoded by a single gene and consists of seven catalytic domains and is functional as a homodimer. It is overexpressed in some NEOPLASMS and is a target in humans of some ANTINEOPLASTIC AGENTS and some ANTI-OBESITY AGENTS.
Preferred term Fatty Acid Synthase, Type I
Fatty Acid Synthase, Mammalian - Narrower
Concept UI M0508622
Preferred term Fatty Acid Synthase, Mammalian
Fatty Acid Synthase, Animal Form - Narrower
Concept UI M0581866
Preferred term Fatty Acid Synthase, Animal Form



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