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Descriptor English: Growth Differentiation Factor 3
Descriptor Spanish: Factor 3 de Diferenciación de Crecimiento
Descriptor factor 3 de diferenciación del crecimiento
Entry term(s) GDF-3
Scope note: Factor de diferenciación del crecimiento que puede desempeñar un papel en el  mantenimiento del estado indiferenciado de las CÉLULAS MADRE PLURIPOTENTES mediante la inhibición de las acciones de las PROTEÍNAS MORFOGENÉTICAS ÓSEAS. El factor 3 de diferenciación también se considera un ligando de señalización nodal que influye en la génesis de la asimetría izquierda-derecha. 
Descriptor Portuguese: Fator 3 de Diferenciação de Crescimento
Descriptor French: Facteur-3 de croissance et de différenciation
Entry term(s): GDF-3
Tree number(s): D12.644.276.954.300.300
D12.644.276.954.550.300
D12.776.467.942.300.300
D12.776.467.942.550.300
D23.529.942.300.300
D23.529.942.550.300
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D055451
Scope note: A growth differentiation factor that may play a role in maintaining the undifferentiated state of PLURIPOTENT STEM CELLS by inhibiting the actions of BONE MORPHOGENETIC PROTEINS. Differentiation factor 3 is also considered a nodal signaling ligand that influences the genesis of left-right asymmetry.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2009; GROWTH DIFFERENTIATION FACTOR 3 was indexed under INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS 2003-2008, & under GROWTH SUBSTANCES 1993-2002
History Note: 2009(1993)
DeCS ID: 53140
Unique ID: D055451
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2009/01/01
Date of Entry: 2008/07/08
Growth Differentiation Factor 3 - Preferred
Concept UI M0212949
Scope note A growth differentiation factor that may play a role in maintaining the undifferentiated state of PLURIPOTENT STEM CELLS by inhibiting the actions of BONE MORPHOGENETIC PROTEINS. Differentiation factor 3 is also considered a nodal signaling ligand that influences the genesis of left-right asymmetry.
Preferred term Growth Differentiation Factor 3
Entry term(s) GDF-3



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