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Descriptor English: Nodal Signaling Ligands
Descriptor Spanish: Ligandos de Señalización Nodal
Descriptor ligandos de señalización nodal
Scope note: Miembros de la superfamilia de factores de crecimiento transformantes que participan en la formación del patrón y en la diferenciación durante las etapas de pregastrulación y GASTRULACIÓN de los cordados. Varios ligandos de señalización nodal están específicamente involucrados en la génesis de la asimetría izquierda-derecha durante el desarrollo. El nombre de la familia de proteínas proviene de una región crítica de la LÍNEA PRIMITIVA de los embriones vertebrados denominada NÓDULO DE HENSEN. 
Descriptor Portuguese: Ligantes da Sinalização Nodal
Descriptor French: Ligands de la voie de signalisation Nodal
Entry term(s): Nodal Signaling Proteins
Signaling Proteins, Nodal
Tree number(s): D12.644.276.954.550
D12.776.467.942.550
D23.529.942.550
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D055456
Scope note: Members of the transforming growth factor superfamily that play a role in pattern formation and differentiation during the pregastrulation and GASTRULATION stages of chordate development. Several nodal signaling ligands are specifically involved in the genesis of left-right asymmetry during development. The protein group is named after a critical region of the vertebrate embryo PRIMITIVE STREAK referred to as HENSEN'S NODE.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2009
History Note: 2009
DeCS ID: 53145
Unique ID: D055456
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2009/01/01
Date of Entry: 2008/07/08
Nodal Signaling Ligands - Preferred
Concept UI M0517794
Scope note Members of the transforming growth factor superfamily that play a role in pattern formation and differentiation during the pregastrulation and GASTRULATION stages of chordate development. Several nodal signaling ligands are specifically involved in the genesis of left-right asymmetry during development. The protein group is named after a critical region of the vertebrate embryo PRIMITIVE STREAK referred to as HENSEN'S NODE.
Preferred term Nodal Signaling Ligands
Entry term(s) Nodal Signaling Proteins
Signaling Proteins, Nodal



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