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Descriptor English: Nodal Protein
Descriptor Spanish: Proteína Nodal
Descriptor proteína nodal
Scope note: Miembro fundador de la familia de proteínas de ligandos de señalización nodal. La proteína nodal fue originalmente descubierta en la región de la línea primitiva del embrión del ratón denominada NÓDULO DE HENSEN. Es expresada asimétricamente en el lado izquierdo en los cordados y desempeña un papel crítico en la génesis de la asimetría izquierda-derecha durante el desarrollo de los vertebrados.
Descriptor Portuguese: Proteína Nodal
Descriptor French: Protéine Nodal
Tree number(s): D12.644.276.954.550.650
D12.776.467.942.550.650
D23.529.942.550.650
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D055457
Scope note: The founding member of the nodal signaling ligand family of proteins. Nodal protein was originally discovered in the region of the mouse embryo primitive streak referred to as HENSEN'S NODE. It is expressed asymmetrically on the left side in chordates and plays a critical role in the genesis of left-right asymmetry during vertebrate development.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2009; NODAL PROTEIN was indexed under TRANSFORMING GROWTH FACTOR BETA 1999-2008, & under PROTEINS 1996-1998
History Note: 2009
DeCS ID: 53147
Unique ID: D055457
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2009/01/01
Date of Entry: 2008/07/08
Nodal Protein - Preferred
Concept UI M0517795
Scope note The founding member of the nodal signaling ligand family of proteins. Nodal protein was originally discovered in the region of the mouse embryo primitive streak referred to as HENSEN'S NODE. It is expressed asymmetrically on the left side in chordates and plays a critical role in the genesis of left-right asymmetry during vertebrate development.
Preferred term Nodal Protein



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