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Descriptor English: Retinoblastoma-Binding Protein 2
Descriptor Spanish: Proteína 2 de Unión a Retinoblastoma
Descriptor proteína 2 de unión al retinoblastoma
Scope note: Proteína de unión al retinoblastoma que también es un miembro de las histona desmetilasas que contienen un dominio de Jumonji. Tiene actividad de desmetilación en residuos específicos de LISINA que se encuentran en la HISTONA H3. 
Descriptor Portuguese: Proteína 2 de Ligação ao Retinoblastoma
Descriptor French: Protéine-2 de liaison à la protéine du rétinoblastome
Entry term(s): Jumonji Domain Containing Protein 1A
Jumonji Domain-Containing Protein 1A
Jumonji, AT Rich Interactive Domain 1A
RBBP2 Protein
Retinoblastoma Binding Protein 2
Tree number(s): D08.811.682.662.582.475.500.500
D08.811.682.690.416.388.200
D12.644.360.024.328.200
D12.776.157.057.158.200
D12.776.476.024.420.200
D12.776.660.769.200
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D056485
Scope note: A retinoblastoma binding protein that is also a member of the Jumonji-domain histone demethylases. It has demethylation activity towards specific LYSINE residues found on HISTONE H3.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 1.14.11.27
Previous Indexing: Carrier Proteins (1991-2004)
Intracellular Signaling Peptides and Proteins (2005-2009)
Tumor Suppressor Proteins (2005-2009)
Public MeSH Note: 2010
History Note: 2010
DeCS ID: 53608
Unique ID: D056485
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2010/01/01
Date of Entry: 2009/07/06
Revision Date: 2016/06/28
Retinoblastoma-Binding Protein 2 - Preferred
Concept UI M0527450
Scope note A retinoblastoma binding protein that is also a member of the Jumonji-domain histone demethylases. It has demethylation activity towards specific LYSINE residues found on HISTONE H3.
Preferred term Retinoblastoma-Binding Protein 2
Entry term(s) Jumonji Domain Containing Protein 1A
Jumonji Domain-Containing Protein 1A
Jumonji, AT Rich Interactive Domain 1A
RBBP2 Protein
Retinoblastoma Binding Protein 2



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