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Descriptor English: Retinoblastoma-Binding Protein 4
Descriptor Spanish: Proteína 4 de Unión a Retinoblastoma
Descriptor proteína 4 de unión al retinoblastoma
Scope note: Proteína de unión al retinoblastoma implicada en el ENSAMBLE Y DESENSAMBLE DE CROMATINA, desacetilación de las histonas y represión de la TRANSCRIPCIÓN GENÉTICA. Aunque se descubrió como una proteína de unión al retinoblastoma tiene afinidad por las HISTONAS nucleares (“core”) y es una subunidad de factor 1 del ensamble de la cromatina y del complejo represor policomb 2.
Descriptor Portuguese: Proteína 4 de Ligação ao Retinoblastoma
Descriptor French: Protéine-4 de liaison à la protéine du rétinoblastome
Entry term(s): Chromatin Assembly Factor 1 Subunit C
Nucleosome Remodeling Factor Subunit RBAP48
Nucleosome-Remodeling Factor Subunit RBAP48
RBBP4 Protein
RbAp48 Protein
Retinoblastoma Binding Protein 4
Retinoblastoma p48 Binding Protein
Retinoblastoma p48-Binding Protein
p48 Subunit, Chromatin Assembly Factor 1
p48 Subunit, Chromatin Assembly Factor-1
p48-Binding Protein, Retinoblastoma
Tree number(s): D05.500.781.750.500
D08.811.277.087.520.500.775
D08.811.277.087.520.750.775
D08.811.600.620.775
D08.811.600.795.775
D12.644.360.024.328.600
D12.776.157.057.158.600
D12.776.476.024.420.600
D12.776.580.219.200.500
D12.776.660.235.600.200.500
D12.776.660.769.600
D12.776.664.235.800.200.500
D12.776.930.780.890.200.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D056505
Scope note: A retinoblastoma-binding protein that is involved in CHROMATIN REMODELING, histone deacetylation, and repression of GENETIC TRANSCRIPTION. Although initially discovered as a retinoblastoma binding protein it has an affinity for core HISTONES and is a subunit of chromatin assembly factor-1 and polycomb repressive complex 2.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2010
History Note: 2010
DeCS ID: 53592
Unique ID: D056505
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2010/01/01
Date of Entry: 2009/07/06
Revision Date: 2016/02/18
Retinoblastoma-Binding Protein 4 - Preferred
Concept UI M0527525
Scope note A retinoblastoma-binding protein that is involved in CHROMATIN REMODELING, histone deacetylation, and repression of GENETIC TRANSCRIPTION. Although initially discovered as a retinoblastoma binding protein it has an affinity for core HISTONES and is a subunit of chromatin assembly factor-1 and polycomb repressive complex 2.
Preferred term Retinoblastoma-Binding Protein 4
Entry term(s) Chromatin Assembly Factor 1 Subunit C
Nucleosome Remodeling Factor Subunit RBAP48
Nucleosome-Remodeling Factor Subunit RBAP48
RBBP4 Protein
RbAp48 Protein
Retinoblastoma Binding Protein 4
Retinoblastoma p48 Binding Protein
Retinoblastoma p48-Binding Protein
p48 Subunit, Chromatin Assembly Factor 1
p48 Subunit, Chromatin Assembly Factor-1
p48-Binding Protein, Retinoblastoma



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