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Descriptor English: Jumonji Domain-Containing Histone Demethylases
Descriptor Spanish: Histona Demetilasas con Dominio de Jumonji
Descriptor histona desmetilasas que contienen el dominio jumonji
Scope note: Familia de histonas desmetilasas que comparten un dominio conservado Jumonji C. Las enzimas funcionan a través de un mecanismo de dioxigenasa dependiente de hierro que acopla la conversión del 2-oxoglutarato a succinato a la hidroxilación de los grupos N-metilo.
Descriptor Portuguese: Histona Desmetilases com o Domínio Jumonji
Descriptor French: Jumonji Domain-Containing Histone Demethylases
Entry term(s): JmjC Domain Containing Histone Demethylases
JmjC Domain-Containing Histone Demethylases
Jumonji Domain Containing Histone Demethylases
Tree number(s): D08.811.682.662.582.475.500
D08.811.682.690.416.388
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D056484
Scope note: A family of histone demethylases that share a conserved Jumonji C domain. The enzymes function via an iron-dependent dioxygenase mechanism that couples the conversion of 2-oxoglutarate to succinate to the hydroxylation of N-methyl groups.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 1.14.11.-
Public MeSH Note: 2010
History Note: 2010
DeCS ID: 53607
Unique ID: D056484
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2010/01/01
Date of Entry: 2009/07/06
Jumonji Domain-Containing Histone Demethylases - Preferred
Concept UI M0527449
Scope note A family of histone demethylases that share a conserved Jumonji C domain. The enzymes function via an iron-dependent dioxygenase mechanism that couples the conversion of 2-oxoglutarate to succinate to the hydroxylation of N-methyl groups.
Preferred term Jumonji Domain-Containing Histone Demethylases
Entry term(s) JmjC Domain Containing Histone Demethylases
JmjC Domain-Containing Histone Demethylases
Jumonji Domain Containing Histone Demethylases



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