Descriptor English: | NAV1.5 Voltage-Gated Sodium Channel | ||||||
Descriptor Spanish: |
Canal de Sodio Activado por Voltaje NAV1.5
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Descriptor Portuguese: | Canal de Sódio Disparado por Voltagem NAV1.5 | ||||||
Descriptor French: | Canal sodique voltage-dépendant NAV1.5 | ||||||
Entry term(s): |
NAV1.5 Voltage Gated Sodium Channel SCN5A Sodium Channel alpha Subunit Sodium Channel Protein Type 5 Subunit alpha Sodium Channel, Voltage-Gated, Type V, alpha Subunit Type 5 Voltage Gated Sodium Channel Type 5 Voltage-Gated Sodium Channel Voltage Gated Sodium Channel Type 5 Voltage Gated Sodium Channel Type 5 Subunit alpha Voltage-Gated Na+ Channel Na(v)1.5a Voltage-Gated Sodium Channel Type 5 Voltage-Gated Sodium Channel Type 5 Subunit alpha |
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Tree number(s): |
D12.776.157.530.400.875.750.500 D12.776.543.550.450.875.750.500 D12.776.543.585.400.875.750.500 D12.776.631.960.500 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D062554 | ||||||
Scope note: | A voltage-gated sodium channel subtype that mediates the sodium ion PERMEABILITY of CARDIOMYOCYTES. Defects in the SCN5A gene, which codes for the alpha subunit of this sodium channel, are associated with a variety of CARDIAC DISEASES that result from loss of sodium channel function. |
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Allowable Qualifiers: |
AD administration & dosage AE adverse effects AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Entry Combination: |
antagonists & inhibitors:Voltage-Gated Sodium Channel Blockers
agonists:Voltage-Gated Sodium Channel Agonists |
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Previous Indexing: |
Sodium Channels (2002-2012) |
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Public MeSH Note: | 2013; SODIUM CHANNEL PROTEIN TYPE 5 SUBUNIT ALPHA (now NAV1.5 VOLTAGE-GATED SODIUM CHANNEL) was indexed under SODIUM CHANNELS 2002-2012 |
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History Note: | 2013 |
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DeCS ID: | 54951 | ||||||
Unique ID: | D062554 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 2013/01/01 | ||||||
Date of Entry: | 2012/07/03 | ||||||
Revision Date: | 2016/07/01 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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NAV1.5 Voltage-Gated Sodium Channel
- Preferred
Voltage-Gated Sodium Channel Type 5 Subunit alpha
- Narrower
Concept UI |
M0568593 |
Scope note | A voltage-gated sodium channel subtype that mediates the sodium ion PERMEABILITY of CARDIOMYOCYTES. Defects in the SCN5A gene, which codes for the alpha subunit of this sodium channel, are associated with a variety of CARDIAC DISEASES that result from loss of sodium channel function. |
Preferred term | NAV1.5 Voltage-Gated Sodium Channel |
Entry term(s) |
NAV1.5 Voltage Gated Sodium Channel Type 5 Voltage Gated Sodium Channel Type 5 Voltage-Gated Sodium Channel Voltage Gated Sodium Channel Type 5 Voltage-Gated Sodium Channel Type 5 |
Concept UI |
M0568577 |
Preferred term | Voltage-Gated Sodium Channel Type 5 Subunit alpha |
Entry term(s) |
SCN5A Sodium Channel alpha Subunit Sodium Channel Protein Type 5 Subunit alpha Sodium Channel, Voltage-Gated, Type V, alpha Subunit Voltage Gated Sodium Channel Type 5 Subunit alpha Voltage-Gated Na+ Channel Na(v)1.5a |
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