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Descriptor English: NAV1.8 Voltage-Gated Sodium Channel
Descriptor Spanish: Canal de Sodio Activado por Voltaje NAV1.8
Descriptor canales del sodio dependientes de voltaje NAV1.8
Entry term(s) subunidad alfa tipo 10 de los canales del sodio dependientes de voltaje
Scope note: Subtipo de canal del sodio dependiente de voltaje que se expresa en los nociceptores, incluidas las neuronas sensitivas del trigémino y de la médula. Interviene en la transmisión de las señales dolorosas inducidas por el frío, el calor, y los estímulos mecánicos.
Descriptor Portuguese: Canal de Sódio Disparado por Voltagem NAV1.8
Descriptor French: Canal sodique voltage-dépendant NAV1.8
Entry term(s): NAV1.8 Voltage Gated Sodium Channel
PN3 Sodium Channel
Peripheral Nerve Sodium Channel 3
SCN10A Sodium Channel alpha Subunit
Sodium Channel Protein Type 10 Subunit alpha
Sodium Channel Protein Type X
Sodium Channel, PN3
Type 10 Voltage Gated Sodium Channel
Type 10 Voltage-Gated Sodium Channel
Voltage Gated Sodium Channel Type 10
Voltage Gated Sodium Channel Type 10 Subunit alpha
Voltage-Gated Sodium Channel Type 10
Voltage-Gated Sodium Channel Type 10 Subunit alpha
Tree number(s): D12.776.157.530.400.875.750.800
D12.776.543.550.450.875.750.800
D12.776.543.585.400.875.750.800
D12.776.631.960.800
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D062559
Scope note: A voltage-gated sodium channel subtype that is expressed in nociceptors, including spinal and trigeminal sensory neurons. It plays a role in the transmission of pain signals induced by cold, heat, and mechanical stimuli.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Entry Combination: antagonists & inhibitors:Voltage-Gated Sodium Channel Blockers
agonists:Voltage-Gated Sodium Channel Agonists
Previous Indexing: Sodium Channels (1996-2012)
Public MeSH Note: 2013; SENSORY NEURON SPECIFIC (SNS) SODIUM CHANNEL (now NAV1.8 VOLTAGE-GATED SODIUM CHANNEL) was indexed under SODIUM CHANNELS 1996-2012
History Note: 2013
DeCS ID: 54954
Unique ID: D062559
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2013/01/01
Date of Entry: 2012/07/03
Revision Date: 2016/07/01
NAV1.8 Voltage-Gated Sodium Channel - Preferred
Concept UI M0568590
Scope note A voltage-gated sodium channel subtype that is expressed in nociceptors, including spinal and trigeminal sensory neurons. It plays a role in the transmission of pain signals induced by cold, heat, and mechanical stimuli.
Preferred term NAV1.8 Voltage-Gated Sodium Channel
Entry term(s) NAV1.8 Voltage Gated Sodium Channel
PN3 Sodium Channel
Peripheral Nerve Sodium Channel 3
Sodium Channel Protein Type X
Sodium Channel, PN3
Type 10 Voltage Gated Sodium Channel
Type 10 Voltage-Gated Sodium Channel
Voltage Gated Sodium Channel Type 10
Voltage-Gated Sodium Channel Type 10
Sodium Channel Protein Type 10 Subunit alpha - Narrower
Concept UI M0560987
Preferred term Sodium Channel Protein Type 10 Subunit alpha
Entry term(s) SCN10A Sodium Channel alpha Subunit
Voltage Gated Sodium Channel Type 10 Subunit alpha
Voltage-Gated Sodium Channel Type 10 Subunit alpha



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