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Descriptor English: Claudin-2
Descriptor Spanish: Claudina-2
Descriptor claudina 2
Scope note: Subtipo de claudina que se asocia a la formación de canales selectivos de cationes e incremento de la permeabilidad epitelial. Se localiza en las UNIONES ESTRECHAS de los TÚBULOS RENALES PROXIMALES y del EPITELIO INTESTINAL.
Descriptor Portuguese: Claudina-2
Descriptor French: Claudine-2
Entry term(s): Claudin 2
Tree number(s): D12.776.543.940.200.200
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D062446
Scope note: A claudin subtype that is associated with the formation of cation-selective channels and increased epithelial permeability. It is localized to the TIGHT JUNCTIONS of the PROXIMAL KIDNEY TUBULE and INTESTINAL EPITHELIUM.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Claudins (2004-2012)
Public MeSH Note: 2013
History Note: 2013
DeCS ID: 54978
Unique ID: D062446
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2013/01/01
Date of Entry: 2012/07/03
Revision Date: 2016/01/15
Claudin-2 - Preferred
Concept UI M0568463
Scope note A claudin subtype that is associated with the formation of cation-selective channels and increased epithelial permeability. It is localized to the TIGHT JUNCTIONS of the PROXIMAL KIDNEY TUBULE and INTESTINAL EPITHELIUM.
Preferred term Claudin-2
Entry term(s) Claudin 2



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