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Descriptor English: Claudin-5
Descriptor Spanish: Claudina-5
Descriptor claudina 5
Scope note: Subtipo de claudina que se localiza en las UNIONES ESTRECHAS de las CÉLULAS ENDOTELIALES VASCULARES. Esta proteína se identificó inicialmente como una de las varias proteínas ausentes en el SÍNDROME VELOCARDIOFACIAL y puede tener un importante papel en el mantenimiento de la BARRERA HEMATOENCEFÁLICA.
Descriptor Portuguese: Claudina-5
Descriptor French: Claudine-5
Entry term(s): Claudin 5
TMVCF Protein
Transmembrane Protein Deleted in Velocardiofacial Syndrome
Tree number(s): D12.776.543.940.200.500
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D062507
Scope note: A claudin subtype that is found localized to TIGHT JUNCTIONS in VASCULAR ENDOTHELIAL CELLS. The protein was initially identified as one of several proteins which are deleted in VELOCARDIOFACIAL SYNDROME and may play an important role in maintaining the integrity of the BLOOD-BRAIN BARRIER.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Claudins (2011-2012)
Membrane Proteins (1997-2010)
Public MeSH Note: 2013
History Note: 2013
Related: DiGeorge Syndrome MeSH
DeCS ID: 54981
Unique ID: D062507
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2013/01/01
Date of Entry: 2012/07/03
Revision Date: 2016/01/15
Claudin-5 - Preferred
Concept UI M0568519
Scope note A claudin subtype that is found localized to TIGHT JUNCTIONS in VASCULAR ENDOTHELIAL CELLS. The protein was initially identified as one of several proteins which are deleted in VELOCARDIOFACIAL SYNDROME and may play an important role in maintaining the integrity of the BLOOD-BRAIN BARRIER.
Preferred term Claudin-5
Entry term(s) Claudin 5
TMVCF Protein
Transmembrane Protein Deleted in Velocardiofacial Syndrome



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