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Descriptor English: Claudin-4
Descriptor Spanish: Claudina-4
Descriptor claudina 4
Entry term(s) claudina4
Scope note: Subtipo de claudina que interviene en la propiedad de formación de barrera de las UNIONES ESTRECHAS. La claudina-4 se asocia a la claudina-8 en los CONDUCTOS RENALES COLECTORES donde interviene en la reabsorción paracelular de iones cloruro.
Descriptor Portuguese: Claudina-4
Descriptor French: Claudine-4
Entry term(s): Claudin 4
Claudin4
Tree number(s): D12.776.543.940.200.400
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D062506
Scope note: A claudin subtype that takes part in maintaining the barrier-forming property of TIGHT JUNCTIONS. Claudin-4 is found associated with CLAUDIN-8 in the KIDNEY COLLECTING DUCT where it may play a role in paracellular chloride ion reabsorption.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2013: CLAUDIN-4 was indexed under CLAUDINS (199-2012)
History Note: 2013
DeCS ID: 54980
Unique ID: D062506
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2013/01/01
Date of Entry: 2012/07/03
Revision Date: 2016/01/15
Claudin-4 - Preferred
Concept UI M0568518
Scope note A claudin subtype that takes part in maintaining the barrier-forming property of TIGHT JUNCTIONS. Claudin-4 is found associated with CLAUDIN-8 in the KIDNEY COLLECTING DUCT where it may play a role in paracellular chloride ion reabsorption.
Preferred term Claudin-4
Entry term(s) Claudin 4
Claudin4



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