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Descriptor English: Claudin-3
Descriptor Spanish: Claudina-3
Descriptor claudina 3
Scope note: Subtipo de claudina que se expresa de forma ubicua y actúa como proteína general formadora de barreras en las UNIONES ESTRECHAS. Existe una elevada expresión de claudina-3 en diversos tipos de tumores, lo que sugiere la posibilidad de diana terapéutica para ANTINEOPLÁSICOS específicos.
Descriptor Portuguese: Claudina-3
Descriptor French: Claudine-3
Entry term(s): Claudin 3
Tree number(s): D12.776.543.940.200.300
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D062465
Scope note: A ubiquitously-expressed claudin subtype that acts as a general barrier-forming protein in TIGHT JUNCTIONS. Elevated expression of claudin-3 is found in a variety of tumor cell types, suggesting its role as a therapeutic target for specific ANTINEOPLASTIC AGENTS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Public MeSH Note: 2013; CLAUDIN-3 was indexed under CLAUDINS 1999-2012
History Note: 2013
DeCS ID: 54979
Unique ID: D062465
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2013/01/01
Date of Entry: 2012/07/03
Revision Date: 2016/01/15
Claudin-3 - Preferred
Concept UI M0568484
Scope note A ubiquitously-expressed claudin subtype that acts as a general barrier-forming protein in TIGHT JUNCTIONS. Elevated expression of claudin-3 is found in a variety of tumor cell types, suggesting its role as a therapeutic target for specific ANTINEOPLASTIC AGENTS.
Preferred term Claudin-3
Entry term(s) Claudin 3



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