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Descriptor English: Canagliflozin
Descriptor Spanish: Canagliflozina
Descriptor Portuguese: Canagliflozina
Descriptor French: Canagliflozine
Entry term(s): 1-(Glucopyranosyl)-4-methyl-3-(5-(4-fluorophenyl)-2-thienylmethyl)benzene - T777973
Canagliflozin Hemihydrate
Canagliflozin, Anhydrous
Invokana
Tree number(s): D02.886.778.075
D03.383.903.075
D09.408.348.113
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000068896
Scope note: A glucoside-derived SODIUM-GLUCOSE TRANSPORTER 2 inhibitor that stimulates urinary excretion of glucose by suppressing renal glucose reabsorption. It is used to manage BLOOD GLUCOSE levels in patients with TYPE 2 DIABETES.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Sodium-Glucose Transporter 2 Inhibitors
Registry Number: 0SAC974Z85
Public MeSH Note: 2016; CANAGLIFLOZIN was indexed under GLUCOSIDES and THIOPHENES 2014-2015
History Note: 2016 (2014)
DeCS ID: 55908
Unique ID: D000068896
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2016/01/01
Date of Entry: 2015/07/01
Revision Date: 2018/02/28
Canagliflozin - Preferred
Concept UI M0550188
Scope note A glucoside-derived SODIUM-GLUCOSE TRANSPORTER 2 inhibitor that stimulates urinary excretion of glucose by suppressing renal glucose reabsorption. It is used to manage BLOOD GLUCOSE levels in patients with TYPE 2 DIABETES.
Preferred term Canagliflozin
Invokana - Narrower
Concept UI M000604077
Preferred term Invokana
Canagliflozin Hemihydrate - Narrower
Concept UI M000638386
Preferred term Canagliflozin Hemihydrate
Canagliflozin, Anhydrous - Related but not broader or narrower
Concept UI M000613688
Preferred term Canagliflozin, Anhydrous
Entry term(s) 1-(Glucopyranosyl)-4-methyl-3-(5-(4-fluorophenyl)-2-thienylmethyl)benzene - T777973



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