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Descriptor English: Pyrantel
Descriptor Spanish: Pirantel
Descriptor Portuguese: Pirantel
Descriptor French: Pyrantel
Tree number(s): D02.886.778.634
D03.383.742.634
D03.383.903.634
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D011715
Scope note: A depolarizing neuromuscular-blocking agent, that causes persistent nicotinic activation resulting in spastic paralysis of susceptible nematodes. It is a drug of second-choice after benzimidazoles for treatment of ascariasis, hookworm, and pinworm infections, being effective after a single dose. (From Smith and Reynard, Textbook of Pharmacology, 1992, p920)
Annotation: an antinematodal agent
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antinematodal Agents
Neuromuscular Depolarizing Agents
Registry Number: 4QIH0N49E7
CAS Type 1 Name: Pyrimidine, 1,4,5,6-tetrahydro-1-methyl-2-(2-(2-thienyl)ethenyl)-, (E)-
Public MeSH Note: 74
History Note: 74
DeCS ID: 12151
Unique ID: D011715
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1974/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/31
Pyrantel - Preferred
Concept UI M0018221
Scope note A depolarizing neuromuscular-blocking agent, that causes persistent nicotinic activation resulting in spastic paralysis of susceptible nematodes. It is a drug of second-choice after benzimidazoles for treatment of ascariasis, hookworm, and pinworm infections, being effective after a single dose. (From Smith and Reynard, Textbook of Pharmacology, 1992, p920)
Preferred term Pyrantel



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