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Descriptor English: Ketotifen
Descriptor Spanish: Cetotifen
Descriptor Portuguese: Cetotifeno
Descriptor French: Kétotifène
Entry term(s): 4,9-Dihydro-4-(1-methyl-4-piperidylidene)-10H-benzo(4,5)-cyclohepta(1,2-b)thiophen-10-one
Fumarate, Ketotifen
Ketotifen Fumarate
Ketotifene
Ketotiphen
Ketotiphene
Zaditen
Tree number(s): D02.886.778.370
D03.383.621.370
D03.383.903.370
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D007665
Scope note: A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
Annotation:
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antipruritics
Histamine H1 Antagonists
Anti-Allergic Agents
Registry Number: X49220T18G
CAS Type 1 Name: 10H-Benzo(4,5)cyclohepta(1,2-b)thiophen-10-one, 4,9-dihydro-4-(1-methyl-4-piperidinylidene)-
Previous Indexing: Piperidines (1966-1981)
Thiophenes (1966-1981)
Public MeSH Note: 82
History Note: 82
DeCS ID: 7834
Unique ID: D007665
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1982/01/01
Date of Entry: 1981/05/13
Revision Date: 2016/05/31
Ketotifen - Preferred
Concept UI M0012002
Scope note A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.
Preferred term Ketotifen
Entry term(s) 4,9-Dihydro-4-(1-methyl-4-piperidylidene)-10H-benzo(4,5)-cyclohepta(1,2-b)thiophen-10-one
Ketotifene
Ketotiphen
Ketotiphene
Zaditen - Narrower
Concept UI M0012003
Preferred term Zaditen
Ketotifen Fumarate - Narrower
Concept UI M0361710
Preferred term Ketotifen Fumarate
Entry term(s) Fumarate, Ketotifen



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