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Descriptor English: Tartrate-Resistant Acid Phosphatase
Descriptor Spanish: Fosfatasa Ácida Tartratorresistente
Descriptor fosfatasa ácida tartratorresistente
Entry term(s) AcPasa 5 tipo TRAP
AcPasa V
TRAcP
fosfatasa ácida V
fosfatasa ácida resistente al tartrato
fosfatasa ácida resistente al tartrato tipo 5
fosfatasa ácida tartratorresistente tipo 5
fosfatasa ácida tipo 5
uteroferrina
Scope note: Es una de las diferentes fosfatasas ácidas de humanos, otros mamíferos, plantas y algunos procariotas. La proteína plegada de la fosfatasa ácida resistente a tartrato se parece a la del dominio catalítico de la fosfatasa ácida púrpura de plantas y de otras serina-treonina proteína fosfatasas, que también contienen un dominio metalofosfoesterasa. Un gen produce las diferentes formas que incluyen la fosfatasa ácida púrpura del bazo y otros tejidos. La fosfatasa ácida resistente al tartrato es un biomarcador de estados patológicos en los que se sobreexpresa. Estas afecciones incluyen la ENFERMEDAD DE GAUCHER, la ENFERMEDAD DE HODKING, la RESORCIÓN ÓSEA y las METÁSTASIS.
Descriptor Portuguese: Fosfatase Ácida Resistente a Tartarato
Descriptor French: Tartrate-resistant acid phosphatase
Entry term(s): AcPase V
Acid Phosphatase V
Acid Phosphatase, Tartrate-Resistant
Phosphatase V, Acid
Phosphatase, Tartrate-Resistant Acid
TRAP Type 5 AcPase
TRAcP
Tartrate Resistant Acid Phosphatase
Tartrate Resistant Acid Phosphatase Type 5
Tartrate-Resistant Acid Phosphatase Type 5
Type 5 Acid Phosphatase
Uteroferrin
V, AcPase
V, Acid Phosphatase
Tree number(s): D08.811.277.352.650.025.500
D08.811.277.352.650.625.862
D12.776.476.559.862
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000071681
Scope note: One of several acid phosphatases in humans, other mammals, plants, and a few prokaryotes. The protein fold of tartrate-resistant acid phosphatase (TRAP) resembles that of the catalytic domain of plant purple acid phosphatase and other serine/threonine-protein phosphatases that also contain a metallophosphoesterase domain. One gene produces the various forms which include purple acid phosphatases from spleen and other tissues. Tartrate-resistant acid phosphatase is a biomarker for pathological states in which it is over-expressed. Such conditions include GAUCHER DISEASE; HODGKIN DISEASE; BONE RESORPTION; and NEOPLASM METASTASIS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.1.3.2
Public MeSH Note: 2017; TARTRATE-RESISTANT ACID PHOSPHATASE was indexed under ACID PHOSPHATASE and ISOENZYMES 1995-2016
History Note: 2017 (1995)
DeCS ID: 56474
Unique ID: D000071681
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/06/30
Tartrate-Resistant Acid Phosphatase - Preferred
Concept UI M0246521
Scope note One of several acid phosphatases in humans, other mammals, plants, and a few prokaryotes. The protein fold of tartrate-resistant acid phosphatase (TRAP) resembles that of the catalytic domain of plant purple acid phosphatase and other serine/threonine-protein phosphatases that also contain a metallophosphoesterase domain. One gene produces the various forms which include purple acid phosphatases from spleen and other tissues. Tartrate-resistant acid phosphatase is a biomarker for pathological states in which it is over-expressed. Such conditions include GAUCHER DISEASE; HODGKIN DISEASE; BONE RESORPTION; and NEOPLASM METASTASIS.
Preferred term Tartrate-Resistant Acid Phosphatase
Entry term(s) Acid Phosphatase, Tartrate-Resistant
Phosphatase, Tartrate-Resistant Acid
TRAcP
Tartrate Resistant Acid Phosphatase
TRAP Type 5 AcPase - Narrower
Concept UI M000618272
Preferred term TRAP Type 5 AcPase
Entry term(s) AcPase V
Acid Phosphatase V
Phosphatase V, Acid
Tartrate Resistant Acid Phosphatase Type 5
Tartrate-Resistant Acid Phosphatase Type 5
Type 5 Acid Phosphatase
V, AcPase
V, Acid Phosphatase
Uteroferrin - Narrower
Concept UI M000617677
Preferred term Uteroferrin



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