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Descriptor English: 12E7 Antigen
Descriptor Spanish: Antígeno 12E7
Descriptor antígeno 12E7
Entry term(s) CD99
antígeno CD99
antígeno E2
antígenos CD99
glucoproteína E2 de la superficie de las células T
glucoproteína de superficie E2 de célula T
molécula CD99
proteína 12E7
proteína MIC2
Scope note: Molécula de adhesión celular que en el ser humano está codificada por un gen en la REGIÓN PSEUDOAUTOSÓMICA de los CROMOSOMAS SEXUALES. Está implicada en la ADHESIÓN CELULAR de los LINFOCITOS T y en la FORMACIÓN DE ROSETAS de ERITROCITOS. También participa en la migración de los LEUCOCITOS a través de la MEMBRANA BASAL del ENDOTELIO. El antígeno 12E7 se localiza junto a PECAM-1 pero funciona de manera independiente.
Descriptor Portuguese: Antígeno 12E7
Descriptor French: Antigène CD99
Entry term(s): 12E7 Protein
Antigen, 12E7
Antigen, CD99
Antigen, E2
Antigens, CD99
CD99 Antigen
CD99 Antigens
CD99 Molecule
E2 Antigen
MIC2 Protein
T Cell Surface Glycoprotein E2
T-Cell Surface Glycoprotein E2
Tree number(s): D09.400.430.890.200.049
D12.776.395.550.200.049
D12.776.543.550.200.062
D23.050.301.350.049
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000071443
Scope note: A cell adhesion molecule that, in humans, is encoded by a gene on the PSEUDOAUTOSOMAL REGION of SEX CHROMOSOMES. It functions in CELL ADHESION of T-LYMPHOCYTES and ROSETTE FORMATION by ERYTHROCYTES. It is also involved in the migration of LEUKOCYTES through the ENDOTHELIUM BASEMENT MEMBRANE. The 12E7 antigen co-localizes with, but functions independently of PECAM-1.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Previous Indexing: Antigens, CD (2004-2016)
Cell Adhesion Molecules (2004-2016)
Public MeSH Note: 2018; see ANTIGENS, CD99 2017-2018
History Note: 2018 (2017)
DeCS ID: 56621
Unique ID: D000071443
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2017/05/24
12E7 Antigen - Preferred
Concept UI M000614695
Scope note A cell adhesion molecule that, in humans, is encoded by a gene on the PSEUDOAUTOSOMAL REGION of SEX CHROMOSOMES. It functions in CELL ADHESION of T-LYMPHOCYTES and ROSETTE FORMATION by ERYTHROCYTES. It is also involved in the migration of LEUKOCYTES through the ENDOTHELIUM BASEMENT MEMBRANE. The 12E7 antigen co-localizes with, but functions independently of PECAM-1.
Preferred term 12E7 Antigen
Entry term(s) 12E7 Protein
Antigen, 12E7
Antigen, CD99
Antigen, E2
Antigens, CD99
CD99 Antigen
CD99 Antigens
CD99 Molecule
E2 Antigen
MIC2 Protein
T Cell Surface Glycoprotein E2
T-Cell Surface Glycoprotein E2



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