| Descriptor English: | Cell Adhesion Molecule-1 | ||||||
| Descriptor Spanish: |
Molécula 1 de Adhesión Celular
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| Descriptor Portuguese: | Molécula 1 de Adesão Celular | ||||||
| Descriptor French: | Molécule-1 d'adhésion cellulaire | ||||||
| Entry term(s): |
Adhesion Molecule-1, Cell CADM1 Protein Cell Adhesion Molecule 1 IGSF4 Protein Molecule-1, Cell Adhesion TSLC1 Protein Tumor Suppressor in Lung Cancer 1 Protein |
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| Tree number(s): |
D09.400.430.890.200.115 D12.776.395.550.200.115 D12.776.543.550.200.128 D23.050.301.350.115 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000075982 | ||||||
| Scope note: | A cell adhesion molecule that contains extracellular immunoglobulin V and C2 domains. It mediates homophilic and heterophilic cell-cell adhesion independently of calcium, and acts as a tumor suppressor in NON-SMALL-CELL LUNG CANCER (NSCLC) cells. Its interaction with NATURAL KILLER CELLS is important for their cytotoxicity and its expression by MAST CELLS plays a role in their interaction with neurons; it may also function in synapse assembly, nerve growth and differentiation. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Cell Adhesion Molecules (2000-2017) Immunoglobulins (2000-2017) |
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| Public MeSH Note: | 2018 |
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| History Note: | 2018 |
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| Related: |
Immunoglobulin Domains
MeSH | ||||||
| DeCS ID: | 57123 | ||||||
| Unique ID: | D000075982 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2018/01/01 | ||||||
| Date of Entry: | 2017/07/11 | ||||||
| Revision Date: | 2017/06/29 |
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CHEMICALS AND DRUGS
Carbohydrates [D09]Carbohydrates -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Biological Factors [D23]Biological Factors
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Cell Adhesion Molecule-1
- Preferred
| Concept UI |
M000631735 |
| Scope note | A cell adhesion molecule that contains extracellular immunoglobulin V and C2 domains. It mediates homophilic and heterophilic cell-cell adhesion independently of calcium, and acts as a tumor suppressor in NON-SMALL-CELL LUNG CANCER (NSCLC) cells. Its interaction with NATURAL KILLER CELLS is important for their cytotoxicity and its expression by MAST CELLS plays a role in their interaction with neurons; it may also function in synapse assembly, nerve growth and differentiation. |
| Preferred term | Cell Adhesion Molecule-1 |
| Entry term(s) |
Adhesion Molecule-1, Cell CADM1 Protein Cell Adhesion Molecule 1 IGSF4 Protein Molecule-1, Cell Adhesion TSLC1 Protein Tumor Suppressor in Lung Cancer 1 Protein |
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