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Descriptor English: Patched-2 Receptor
Descriptor Spanish: Receptor Patched-2
Descriptor receptor Patched 2
Entry term(s) homólogo 2 de Patched
proteína PTCH2
proteína Patched-2
receptor Patched-2
Scope note: Receptor patched que puede funcionar de forma redundante con el RECEPTOR PATCHED-1 para modular la vía de señalización de Hedgehog. También puede jugar un papel en el desarrollo epidérmico y como PROTEÍNA SUPRESORA DE TUMORES. Las mutaciones en el gen patched-2 se asocian al SÍNDROME DEL NEVO BASOCELULAR, al CARCINOMA BASOCELULAR y al MEDULOBLASTOMA.
Descriptor Portuguese: Receptor Patched-2
Descriptor French: Récepteur Patched-2
Entry term(s): PTCH2 Protein
Patched 2 Protein
Patched 2 Receptor
Patched Homolog 2
Patched Homolog-2
Patched Receptor 2
Patched Receptor-2
Patched-2 Protein
Receptor, Patched-2
Tree number(s): D12.776.543.750.058.750
D12.776.624.776.633.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000072082
Scope note: A patched receptor that may function redundantly with the PATCHED-1 RECEPTOR to modulate hedgehog signaling. It may also play a role in epidermal development and as a TUMOR SUPPRESSOR PROTEIN. Mutations in the patched-2 gene are associated with BASAL CELL NEVUS SYNDROME; CARCINOMA, BASAL CELL; and MEDULLOBLASTOMA.
Allowable Qualifiers: AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Public MeSH Note: 2017; 2017; PATCHED-2 RECEPTOR was indexed under RECEPTORS, CELL SURFACE 2005-2016, and under MEMBRANE PROTEINS 1996-2005
History Note: 2017 (1996)
DeCS ID: 56642
Unique ID: D000072082
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/05/27
Patched-2 Receptor - Preferred
Concept UI M000616307
Scope note A patched receptor that may function redundantly with the PATCHED-1 RECEPTOR to modulate hedgehog signaling. It may also play a role in epidermal development and as a TUMOR SUPPRESSOR PROTEIN. Mutations in the patched-2 gene are associated with BASAL CELL NEVUS SYNDROME; CARCINOMA, BASAL CELL; and MEDULLOBLASTOMA.
Preferred term Patched-2 Receptor
Entry term(s) PTCH2 Protein
Patched 2 Protein
Patched 2 Receptor
Patched Homolog 2
Patched Homolog-2
Patched Receptor 2
Patched Receptor-2
Patched-2 Protein
Receptor, Patched-2



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