| Descriptor English: | Niemann-Pick C1 Protein | ||||||
| Descriptor Spanish: |
Proteína Niemann-Pick C1
| ||||||
| Descriptor Portuguese: | Proteína C1 de Niemann-Pick | ||||||
| Descriptor French: | Protéine NPC1 | ||||||
| Entry term(s): |
NPC1 Protein Niemann Pick C1 Protein |
||||||
| Tree number(s): |
D12.776.157.530.594 D12.776.543.585.594 D12.776.543.750.058.250 D12.776.543.750.830.235 D12.776.624.776.633.250 |
||||||
| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000077296 | ||||||
| Scope note: | A transmembrane intracellular lipid transporter that helps trafficking lipids, particularly cholesterol, from late endosome/lysosome to the ER and plasma membrane. It may also play a role in other cellular cholesterol homeostasis and is an endosomal entry receptor for filoviruses including EBOLAVIRUS. Mutations in the NPC1 are associated with type C NIEMANN-PICK DISEASE. |
||||||
| Allowable Qualifiers: |
AD administration & dosage AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CH chemistry CL classification DE drug effects DF deficiency GE genetics HI history IM immunology IP isolation & purification ME metabolism PH physiology RE radiation effects TU therapeutic use UL ultrastructure |
||||||
| Previous Indexing: |
Carrier Proteins (1997-2018) Membrane Glycoproteins (1997-2018) |
||||||
| Public MeSH Note: | 2019 |
||||||
| History Note: | 2019 |
||||||
| DeCS ID: | 57596 | ||||||
| Unique ID: | D000077296 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2019/01/01 | ||||||
| Date of Entry: | 2018/07/09 | ||||||
| Revision Date: | 2018/02/28 |
-
-
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
|
|
Niemann-Pick C1 Protein
- Preferred
| Concept UI |
M000640362 |
| Scope note | A transmembrane intracellular lipid transporter that helps trafficking lipids, particularly cholesterol, from late endosome/lysosome to the ER and plasma membrane. It may also play a role in other cellular cholesterol homeostasis and is an endosomal entry receptor for filoviruses including EBOLAVIRUS. Mutations in the NPC1 are associated with type C NIEMANN-PICK DISEASE. |
| Preferred term | Niemann-Pick C1 Protein |
| Entry term(s) |
NPC1 Protein Niemann Pick C1 Protein |
We want your feedback on the new DeCS / MeSH website
We invite you to complete a survey that will take no more than 3 minutes.
Go to survey
