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Descriptor English: Patched Receptors
Descriptor Spanish: Receptores Patched
Descriptor receptores Patched
Entry term(s) proteína Patched
receptor Patched
Scope note: Familia de proteínas transmembranarias que atraviesan la membrana 12 veces, originalmente identificada en la Drosophila, que son receptores para las PROTEÍNAS HEDGEHOG. Juegan un papel importante en la regulación de la PROLIFERACIÓN CELULAR, la DIFERENCIACIÓN CELULAR, la TIPIFICACIÓN DEL CUERPO y también pueden actuar como PROTEÍNAS SUPRESORAS DE TUMORES.
Descriptor Portuguese: Receptores Patched
Descriptor French: Récepteurs patched
Entry term(s): Patched Protein
Patched Receptor
Patched Sonic Hedgehog Receptors
Receptor, Patched
Receptors, Patched
Tree number(s): D12.776.543.750.058
D12.776.624.776.633
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000072079
Scope note: A family of 12-pass transmembrane proteins originally identified in Drosophila that are receptors for HEDGEHOG PROTEINS. They have important roles in regulating CELL PROLIFERATION; CELL DIFFERENTIAION; and BODY PATTERNING and may also function as TUMOR SUPPRESSOR PROTEINS.
Allowable Qualifiers: AD administration & dosage
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CH chemistry
CL classification
DE drug effects
DF deficiency
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PH physiology
RE radiation effects
TU therapeutic use
UL ultrastructure
Public MeSH Note: 2017; PATCHED RECEPTORS was indexed under RECEPTORS, CELL SURFACE 2006-2016 and under MEMBRANE PROTEINS 1996-2005
History Note: 2017 (1996)
DeCS ID: 56640
Unique ID: D000072079
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2017/01/01
Date of Entry: 2016/07/11
Revision Date: 2016/07/11
Patched Receptors - Preferred
Concept UI M000616303
Scope note A family of 12-pass transmembrane proteins originally identified in Drosophila that are receptors for HEDGEHOG PROTEINS. They have important roles in regulating CELL PROLIFERATION; CELL DIFFERENTIAION; and BODY PATTERNING and may also function as TUMOR SUPPRESSOR PROTEINS.
Preferred term Patched Receptors
Entry term(s) Patched Protein
Patched Receptor
Patched Sonic Hedgehog Receptors
Receptor, Patched
Receptors, Patched



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