Search
Descriptor English: NADPH Oxidase 2
Descriptor Spanish: NADPH Oxidasa 2
Descriptor NADPH oxidasa 2
Entry term(s) cadena beta del citocromo B-245
proteína CYBB
proteína GP91-PHOX
proteína NOX2
proteína de la enfermedad granulomatosa crónica
Scope note: Oxidasa NADPH que se expresa en los FAGOCITOS en los que transfiere electrones a través de la membrana plasmática desde el NADPH citosólico al oxígeno molecular exterior. Regula el flujo de protones (H+) a los fagocitos en reposo para el control del pH intracelular. Las mutaciones del gen CYBB se asocian a la ENFERMEDAD GRANULOMATOSA CRÓNICA LIGADA A X.
Descriptor Portuguese: NADPH Oxidase 2
Descriptor French: NADPH Oxidase 2
Entry term(s): CYBB Protein
Chronic Granulomatous Disease Protein
Cytochrome B 245 Beta Chain
Cytochrome B-245 Beta Chain
GP91 PHOX Protein
GP91-PHOX Protein
NOX2 Protein
Oxidase 2, NADPH
Tree number(s): D08.811.682.608.575.875
D12.776.331.894.875
D12.776.543.653.875
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000074662
Scope note: An NADPH oxidase that is expressed by PHAGOCYTES where it transfers electrons across the plasma membrane from cytosolic NADPH to molecular oxygen on the exterior. It regulates proton (H+) flux into resting phagocytes to control intracellular pH. Mutations in the CYBB gene are associated with X-LINKED CHRONIC GRANULOMATOUS DISEASE.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 1.6.3.-
Previous Indexing: Membrane Glycoproteins (1988-2017)
NADPH Oxidases (1997-2017)
Public MeSH Note: 2018
History Note: 2018
DeCS ID: 57024
Unique ID: D000074662
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/04/05
NADPH Oxidase 2 - Preferred
Concept UI M000627303
Scope note An NADPH oxidase that is expressed by PHAGOCYTES where it transfers electrons across the plasma membrane from cytosolic NADPH to molecular oxygen on the exterior. It regulates proton (H+) flux into resting phagocytes to control intracellular pH. Mutations in the CYBB gene are associated with X-LINKED CHRONIC GRANULOMATOUS DISEASE.
Preferred term NADPH Oxidase 2
Entry term(s) CYBB Protein
Chronic Granulomatous Disease Protein
Cytochrome B 245 Beta Chain
Cytochrome B-245 Beta Chain
GP91 PHOX Protein
GP91-PHOX Protein
NOX2 Protein
Oxidase 2, NADPH



We want your feedback on the new DeCS / MeSH website

We invite you to complete a survey that will take no more than 3 minutes.


Go to survey