Descriptor English: | NADPH Oxidase 2 | ||||||
Descriptor Spanish: |
NADPH Oxidasa 2
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Descriptor Portuguese: | NADPH Oxidase 2 | ||||||
Descriptor French: | NADPH Oxidase 2 | ||||||
Entry term(s): |
CYBB Protein Chronic Granulomatous Disease Protein Cytochrome B 245 Beta Chain Cytochrome B-245 Beta Chain GP91 PHOX Protein GP91-PHOX Protein NOX2 Protein Oxidase 2, NADPH |
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Tree number(s): |
D08.811.682.608.575.875 D12.776.331.894.875 D12.776.543.653.875 |
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RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000074662 | ||||||
Scope note: | An NADPH oxidase that is expressed by PHAGOCYTES where it transfers electrons across the plasma membrane from cytosolic NADPH to molecular oxygen on the exterior. It regulates proton (H+) flux into resting phagocytes to control intracellular pH. Mutations in the CYBB gene are associated with X-LINKED CHRONIC GRANULOMATOUS DISEASE. |
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Allowable Qualifiers: |
AD administration & dosage AE adverse effects AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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Registry Number: | EC 1.6.3.- | ||||||
Previous Indexing: |
Membrane Glycoproteins (1988-2017) NADPH Oxidases (1997-2017) |
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Public MeSH Note: | 2018 |
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History Note: | 2018 |
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DeCS ID: | 57024 | ||||||
Unique ID: | D000074662 | ||||||
Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
Date Established: | 2018/01/01 | ||||||
Date of Entry: | 2017/07/11 | ||||||
Revision Date: | 2017/04/05 |
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CHEMICALS AND DRUGS
Enzymes and Coenzymes [D08]Enzymes and Coenzymes -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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NADPH Oxidase 2
- Preferred
Concept UI |
M000627303 |
Scope note | An NADPH oxidase that is expressed by PHAGOCYTES where it transfers electrons across the plasma membrane from cytosolic NADPH to molecular oxygen on the exterior. It regulates proton (H+) flux into resting phagocytes to control intracellular pH. Mutations in the CYBB gene are associated with X-LINKED CHRONIC GRANULOMATOUS DISEASE. |
Preferred term | NADPH Oxidase 2 |
Entry term(s) |
CYBB Protein Chronic Granulomatous Disease Protein Cytochrome B 245 Beta Chain Cytochrome B-245 Beta Chain GP91 PHOX Protein GP91-PHOX Protein NOX2 Protein Oxidase 2, NADPH |
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