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Descriptor English: NADPH Oxidase 1
Descriptor Spanish: NADPH Oxidasa 1
Descriptor NADPH oxidasa 1
Entry term(s) oxidasa mitogénica 1
proteína NOX1
Scope note: Oxidasa NADPH que funciona como canal de protones dependiente de voltaje que se expresa en los FAGOCITOS, especialmente en el colon. Regula el pH intracelular, genera SUPERÓXIDOS tras la activación por la FAGOCITOSIS e interviene en la INMUNIDAD INNATA.
Descriptor Portuguese: NADPH Oxidase 1
Descriptor French: NADPH Oxidase 1
Entry term(s): Mitogenic Oxidase 1
NOX1 Protein
Oxidase 1, Mitogenic
Oxidase 1, NADPH
Tree number(s): D08.811.682.608.575.750
D12.776.331.894.750
D12.776.543.653.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000074624
Scope note: An NADPH oxidase that functions as a voltage-gated proton channel expressed by PHAGOCYTES, especially in the colon. It regulates intracellular pH, generates SUPEROXIDES upon activation by PHAGOCYTOSIS, and may play a role in INNATE IMMUNITY.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 1.6.3.-
Public MeSH Note: 2018; NADPH OXIDASE 1 was indexed under NADH, NADPH OXIDOREDUCTASES 1999-2017
History Note: 2018 (1999)
DeCS ID: 57023
Unique ID: D000074624
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/04/05
NADPH Oxidase 1 - Preferred
Concept UI M000627206
Scope note An NADPH oxidase that functions as a voltage-gated proton channel expressed by PHAGOCYTES, especially in the colon. It regulates intracellular pH, generates SUPEROXIDES upon activation by PHAGOCYTOSIS, and may play a role in INNATE IMMUNITY.
Preferred term NADPH Oxidase 1
Entry term(s) Mitogenic Oxidase 1
NOX1 Protein
Oxidase 1, Mitogenic
Oxidase 1, NADPH



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