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Descriptor English: NADPH Oxidase 5
Descriptor Spanish: NADPH Oxidasa 5
Descriptor NADPH oxidasa 5
Entry term(s) proteína NOX5
Scope note: Oxidasa NADPH que contiene cuatro MOTIVOS EF HAND y se expresa principalmente en los ESPERMATOCITOS y LINFOCITOS así como en las células endoteliales. Funciona como canal de protones dependiente del calcio para generar SUPERÓXIDOS que regulan el crecimiento celular, la APOPTOSIS y la ANGIOGÉNESIS FISIOLÓGICA.
Descriptor Portuguese: NADPH Oxidase 5
Descriptor French: NADPH Oxidase 5
Entry term(s): Nox5 Protein
Tree number(s): D08.811.682.608.575.968
D12.776.331.894.968
D12.776.543.653.968
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000074664
Scope note: An NADPH oxidase that contains four EF HANDS and is expressed primarily by SPERMATOCYTES and LYMPHOCYTES, as well as by endothelial cells. It functions as a calcium-dependent proton channel to generate SUPEROXIDES that regulate cell growth, APOPTOSIS; and PHYSIOLOGIC ANGIOGENESIS.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 1.6.3.-
Previous Indexing: Membrane Proteins (2001-2017)
NADPH Oxidases (2001-2017)
Public MeSH Note: 2018
History Note: 2018
DeCS ID: 57026
Unique ID: D000074664
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/04/05
NADPH Oxidase 5 - Preferred
Concept UI M000627317
Scope note An NADPH oxidase that contains four EF HANDS and is expressed primarily by SPERMATOCYTES and LYMPHOCYTES, as well as by endothelial cells. It functions as a calcium-dependent proton channel to generate SUPEROXIDES that regulate cell growth, APOPTOSIS; and PHYSIOLOGIC ANGIOGENESIS.
Preferred term NADPH Oxidase 5
Entry term(s) Nox5 Protein



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